Alternatives to antibiotics as growth promoters for use in swine production: a review.

Alternatives to antibiotics as growth promoters for use in swine production: a review.
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DOI:
10.1186/2049-1891-4-35
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发表时间:
2013-09-14
影响因子:
7
通讯作者:
Thacker PA
Thacker PA
中科院分区:
农林科学1区
文献类型:
--
作者:
Thacker PA

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在过去的二十年里,大量的研究集中在开发抗生素的替代品,以保持猪的健康和性能。研究最广泛的替代品包括益生菌,益生元,酸化剂,植物提取物和营养品,如铜和锌。由于这些添加剂已在以前的审查中充分涵盖,因此本次审查的重点将放在不太传统的替代品上。讨论了抗菌肽、粘土矿物、蛋黄抗体、精油、桉叶油-中链脂肪酸、稀土元素和重组酶的潜力。基于对文献的全面审查,很明显,存在一长串且不断增长的化合物,这些化合物已被测试其替代抗生素作为猪饲料添加剂的能力。不幸的是,这些化合物中的绝大多数产生不一致的结果,并且很少在其有效性方面与抗生素相同。因此,这一领域似乎仍需要研究,而且抗生素的完美替代品尚不存在。
In the past two decades, an intensive amount of research has been focused on the development of alternatives to antibiotics to maintain swine health and performance. The most widely researched alternatives include probiotics, prebiotics, acidifiers, plant extracts and neutraceuticals such as copper and zinc. Since these additives have been more than adequately covered in previous reviews, the focus of this review will be on less traditional alternatives. The potential of antimicrobial peptides, clay minerals, egg yolk antibodies, essential oils, eucalyptus oil-medium chain fatty acids, rare earth elements and recombinant enzymes are discussed. Based on a thorough review of the literature, it is evident that a long and growing list of compounds exist which have been tested for their ability to replace antibiotics as feed additives in diets fed to swine. Unfortunately, the vast majority of these compounds produce inconsistent results and rarely equal antibiotics in their effectiveness. Therefore, it would appear that research is still needed in this area and that the perfect alternative to antibiotics does not yet exist.
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