Long-term outcomes of cognitive-behavioral treatments for posttraumatic stress disorder among female rape survivors.
Long-term outcomes of cognitive-behavioral treatments for posttraumatic stress disorder among female rape survivors.
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DOI：
10.1037/a0026602
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发表时间：
2012-04
影响因子：
5.9
通讯作者：
Gradus, Jairnie L.
中科院分区：
文献类型：
--
作者：
Resick, Patricia A.;Williams, Lauren F.;Suvak, Michael K.;Monson, Candice M.;Gradus, Jairnie L.
关键词：
我们对一项随机对照试验的参与者进行了长期随访（LTFU）评估，该试验比较了认知加工疗法（CPT）与长期暴露（PE）治疗创伤后应激障碍（PTSD）。积极结果的竞争假设（即，其他治疗，药物）进行了检查。意向治疗（ITT）参与者在参与研究后5-10年进行评估（M = 6.15，SD = 1.22）。我们试图找到171名最初的参与者，这些女性患有创伤后应激障碍，至少经历过一次强奸。在定位的144名参与者中，87.5%（N = 126）进行了重新评估，占原始ITT样本的73.7%。自我报告的PTSD症状是主要结局。临床医师评定的PTSD症状、共病诊断和自我报告的抑郁是次要结局。在整个LTFU期间，由于治疗导致的症状大幅减轻（如中所报告）得以维持，从治疗后到随访期间随时间的变化很小（效应量范围为pr = 0.03至0.14）证明了这一点。在LTFU期间，处理条件之间没有出现显著差异（Cohen d = 0.06-0.29）。ITT诊断检查表明，根据LTFU的临床医生管理PTSD量表，22.2%的CPT和17.5%的PE参与者符合PTSD诊断。改善的维持不能归因于进一步的治疗或药物。CPT和PE导致创伤后应激障碍和相关症状的持久变化，在很长一段时间的女性强奸受害者与广泛的创伤史。
We conducted a long-term follow-up (LTFU) assessment of participants from a randomized controlled trial comparing cognitive processing therapy (CPT) with prolonged exposure (PE) for posttraumatic stress disorder (PTSD). Competing hypotheses for positive outcomes (i.e., additional therapy, medication) were examined. Intention-to-treat (ITT) participants were assessed 5–10 years after participating in the study (M = 6.15, SD = 1.22). We attempted to locate the 171 original participants, women with PTSD who had experienced at least one rape. Of 144 participants located, 87.5% were reassessed (N = 126), which constituted 73.7% of the original ITT sample. Self-reported PTSD symptoms were the primary outcome. Clinician-rated PTSD symptoms, comorbid diagnoses, and self-reported depression were secondary outcomes. Substantial decreases in symptoms due to treatment (as reported in) were maintained throughout the LTFU period, as evidenced by little change over time from posttreatment through follow-up (effect sizes ranging from pr = .03 to .14). No significant differences emerged during the LTFU between the treatment conditions (Cohen’s d = 0.06–0.29). The ITT examination of diagnostics indicated that 22.2% of CPT and 17.5% of PE participants met the diagnosis for PTSD according to the Clinician-Administered PTSD Scale at the LTFU. Maintenance of improvements could not be attributed to further therapy or medications. CPT and PE resulted in lasting changes in PTSD and related symptoms over an extended period of time for female rape victims with extensive histories of trauma.
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影响因子：
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