Reflex conditioning: a new strategy for improving motor function after spinal cord injury.

Reflex conditioning: a new strategy for improving motor function after spinal cord injury.
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DOI:
10.1111/j.1749-6632.2010.05565.x
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发表时间:
2010-06
影响因子:
5.2
通讯作者:
Wolpaw JR
Wolpaw JR
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Chen XY;Chen Y;Wang Y;Thompson A;Carp JS;Segal RL;Wolpaw JR

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脊髓反射调节改变反射大小,诱导脊髓可塑性,并修改运动。适当的反射训练可以改善脊髓损伤后大鼠的行走能力。反射调节为SCI患者的功能恢复提供了一种新的治疗策略。这种方法可以通过靶向特定的反射途径来增加或减少反应性,从而解决SCI患者的特定缺陷。此外,一旦可以实现临床上显著的再生,反射条件反射可以提供一种重新训练新的(可能不完美的)重新连接的脊髓的方法。
Spinal reflex conditioning changes reflex size, induces spinal cord plasticity, and modifies locomotion. Appropriate reflex conditioning can improve walking in rats after spinal cord injury (SCI). Reflex conditioning offers a new therapeutic strategy for restoring function in people with SCI. This approach can address the specific deficits of individuals with SCI by targeting specific reflex pathways for increased or decreased responsiveness. In addition, once clinically significant regeneration can be achieved, reflex conditioning could provide a means of re-educating the newly (and probably imperfectly) reconnected spinal cord.
DOI: 10.1152/jn.00391.2001
发表时间: 2002-02-01
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