Calibration and validation of an innovative approach for estimating general cognitive performance.
Calibration and validation of an innovative approach for estimating general cognitive performance.
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DOI：
10.1159/000357647
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发表时间：
2014
影响因子：
5.7
通讯作者：
Inouye SK
中科院分区：
文献类型：
--
作者：
Gross AL;Jones RN;Fong TG;Tommet D;Inouye SK
为了评估一种创建认知功能综合测量的新方法，我们从现有的神经心理学电池中校准了一种一般认知表现的测量。我们将我们的方法应用于流行病学研究，并将该组合应用于具有全国代表性的老年人样本。对照标准临床诊断对标准效度进行评估。用简易智力状态检查(MMSE)评定收敛效度。在具有全国代表性的老年人样本中，一般认知表现因素的平均值为50，SD=10。大约45分的临界点，对应着23/24的MMSE，最佳地区分了患有和不患有痴呆症的参与者(敏感度=0.94；特异度=0.90；AUC=0.97)。总体认知表现因素在内部是一致的(Cronbach‘s Alpha=0.91)，并提供了广泛认知功能范围内的功能能力的可靠测量。它展示了最小的地板和天花板效应，这比大多数单独的认知测试都有改进。认知复合体是一种高度可靠的测量方法，地板和天花板的影响最小。我们使用具有全国代表性的美国70岁以上成年人样本进行了校准，并建立了与诊断相关的临界点。我们的方法可以用来协调不同环境和研究的神经心理学测试结果。
To evaluate a new approach for creating a composite measure of cognitive function, we calibrated a measure of general cognitive performance from existing neuropsychological batteries. We applied our approach in an epidemiologic study and scaled the composite to a nationally representative sample of older adults. Criterion validity was evaluated against standard clinical diagnoses. Convergent validity was evaluated against the Mini-Mental State Examination (MMSE). The general cognitive performance factor was scaled to have a mean=50 and SD=10 in a nationally representative sample of older adults. A cut-point of approximately 45, corresponding with an MMSE of 23/24, optimally discriminated participants with and without dementia (sensitivity=0.94; specificity=0.90; AUC=0.97). The general cognitive performance factor was internally consistent (Cronbach's alpha=0.91) and provided reliable measures of functional ability across a wide range of cognitive functioning. It demonstrated minimal floor and ceiling effects, which is an improvement over most individual cognitive tests. The cognitive composite is a highly reliable measure, with minimal floor and ceiling effects. We calibrated it using a nationally representative sample of adults over age 70 in the US and established diagnostically relevant cut-points. Our methods can be used to harmonize neuropsychological test results across diverse settings and studies.
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影响因子：
7
作者：
Curran, Patrick J.;Hussong, Andrea M.
通讯作者：
Hussong, Andrea M.
影响因子：
5.7
作者：
Langa, KM;Plassman, BL;Willis, RJ
通讯作者：
Willis, RJ
DOI：
10.1098/rspa.1931.0209
发表时间：
1931-12-01
期刊：
PROCEEDINGS OF THE ROYAL SOCIETY OF LONDON SERIES A-CONTAINING PAPERS OF A MATHEMATICAL AND PHYSICAL CHARACTER
影响因子：
--
作者：
Heywood, HB
通讯作者：
Heywood, HB
影响因子：
3.8
作者：
Jöreskog, KG;Moustaki, I
通讯作者：
Moustaki, I
影响因子：
--
作者：
FEHER, EP;MAHURIN, RK;PIROZZOLO, FJ
通讯作者：
PIROZZOLO, FJ