A novel scratching approach for measuring age-related changes in the in situ toughness of bone.

A novel scratching approach for measuring age-related changes in the in situ toughness of bone.
复制标题

一种新颖的刮擦方法,用于测量与年龄相关的骨原位韧性变化。

DOI:
10.1016/j.jbiomech.2006.06.005
复制
发表时间:
2007
影响因子:
2.4
通讯作者:
Ji,H
Ji,H
中科院分区:
工程技术3区
文献类型:
--
作者:
Wang,X;Yoon,YJ;Ji,H

文献摘要

参考文献

被引文献

相似文献

在这项研究中,提出了使用纳米压痕系统的划痕试验,以评估与年龄相关的变化,在原位骨基质的韧性在超微结构水平。将组织去除能量密度(ur)定义并估计为划痕所做的功(UT)除以划痕凹槽的总体积(us)。我们的值被用来作为一个相对测量的组织在原位韧性。使用该技术测试了来自中年组(49 - 59岁)和老年组(69岁以上)的人皮质骨标本。中年组和老年组的次级骨单位中的估计去除能量密度(us)存在显著差异(分别为5.49±0.696和4.09± 1.30 N/mm 2)。
A scratch test using a nanoindentation system was proposed in this study to assess the age-related changes in the in situ toughness of bone matrix at ultrastructural levels. A tissue removal energy density (ur) was defined and estimated as the work done by the scratch (UT) divided by the total volume of the scratch groove (us). The value of uswas used as a relative measure of the in situ toughness of the tissue. Human cortical bone specimens obtained from middle-aged (between 49 and 59 years old) and elderly groups (over 69 years old) were tested using this technique. A significant difference in the estimated removal energy density (us) in the secondary osteons was found between the middle-aged and elderly groups (5.49±0.696 vs. 4.09±1.30N/mm2, respectively).
DOI: 10.1016/0021-9290(92)90051-2
发表时间: 1992-12-01
影响因子: 2.4
作者:
CHOI, K;GOLDSTEIN, SA
通讯作者: GOLDSTEIN, SA
DOI: 10.1097/00003086-199208000-00041
发表时间: 1992-08
影响因子: 4.2
作者:
A. Boskey
通讯作者: A. Boskey
DOI: 10.1016/s8756-3282(99)00163-5
发表时间: 1999-09-01
期刊: BONE
影响因子: 4.1
作者:
Rho, JY;Zioupos, P;Pharr, GM
通讯作者: Pharr, GM
人类胫骨皮质骨随衰老的结构变化。
DOI: 10.1159/000213871
发表时间: 1997
期刊: Gerontology
影响因子: 3.5
作者:
C. Nyssen;P. Duchesne;A. Dhem
通讯作者: A. Dhem
DOI: 10.1016/0021-9290(89)90013-4
发表时间: 1989-01-01
影响因子: 2.4
作者:
CALER, WE;CARTER, DR
通讯作者: CARTER, DR