Future Prospects of Colorectal Cancer Screening: Characterizing Interval Cancers.
Future Prospects of Colorectal Cancer Screening: Characterizing Interval Cancers.
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DOI：
10.3390/cancers13061328
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发表时间：
2021-03-16
期刊：
影响因子：
5.2
通讯作者：
On Behalf Of The Msic-Sc Research Group
中科院分区：
文献类型：
--
作者：
Ibáñez-Sanz G;Sanz-Pamplona R;Garcia M;On Behalf Of The Msic-Sc Research Group
间隔期结直肠癌的数量是衡量人群筛查计划在降低结直肠癌死亡率方面有效性的中间指标。间隔和筛查检测的癌症之间的差异已经被报道。更好地表征结直肠癌，以区分假阴性粪便免疫化学试验结果与真正的间隔癌症，将有助于确定是否更多地关注筛查计划的组织方面或结直肠癌风险分层。本文综述了间歇性结直肠癌的流行病学、临床和分子特征。未被筛查检测到的肿瘤被称为间隔癌症，并且在筛查事件中的阴性结果之后但在下一次筛查邀请之前被临床诊断。已经研究了与间隔期结直肠癌相关的临床特征，但很少有分子数据可用于描述间隔期结直肠癌。更好地了解与间隔期结直肠癌相关的临床和生物学特征可能会为如何更有效地预防这种疾病提供新的见解。本文就间歇性结直肠癌的流行病学、临床及分子生物学特征进行综述。
The number of interval colorectal cancers is an intermediate measure of the effectiveness of a population-screening programme in decreasing colorectal cancer mortality. Differences between interval and screen-detected cancers have been reported. Better characterization of colorectal cancer to differentiate false-negative faecal immunochemical test results from true interval cancers would help determine whether to focus more on the organizational aspects of a screening programme or on stratifying colorectal cancer risk. This review provides a comprehensive overview of the epidemiological, clinical, and molecular characteristics of interval colorectal cancers. Tumors that are not detected by screening tests are known as interval cancers and are diagnosed clinically after a negative result in the screening episode but before the next screening invitation. Clinical characteristics associated with interval colorectal cancers have been studied, but few molecular data are available that describe interval colorectal cancers. A better understanding of the clinical and biological characteristics associated with interval colorectal cancer may provide new insights into how to prevent this disease more effectively. This review aimed to summarize the current literature concerning interval colorectal cancer and its epidemiological, clinical, and molecular features.
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DOI：
10.1111/hex.12672
发表时间：
2018-08
期刊：
Health expectations : an international journal of public participation in health care and health policy
影响因子：
--
作者：
Barnett KN;Weller D;Smith S;Steele RJ;Vedsted P;Orbell S;Moss SM;Melia JW;Patnick J;Campbell C
通讯作者：
Campbell C
影响因子：
12.6
作者：
Chiu, Han-Mo;Lee, Yi-Chia;Wu, Ming-Shiang
通讯作者：
Wu, Ming-Shiang
DOI：
10.1016/s1470-2045(17)30187-0
发表时间：
2017-06
期刊：
The Lancet. Oncology
影响因子：
--
作者：
Atkin W;Wooldrage K;Brenner A;Martin J;Shah U;Perera S;Lucas F;Brown JP;Kralj-Hans I;Greliak P;Pack K;Wood J;Thomson A;Veitch A;Duffy SW;Cross AJ
通讯作者：
Cross AJ
影响因子：
4.8
作者：
Cisyk, A. L.;Penner-Goeke, S.;Lichtensztejn, Z.;Nugent, Z.;Wightman, R. H.;Singh, H.;McManus, K. J.
通讯作者：
McManus, K. J.
影响因子：
4.5
作者：
Alvarez-Urturi, Cristina;Andreu, Montserrat;Bessa, Xavier
通讯作者：
Bessa, Xavier