Melanoma in situ in a private practice setting 2005 through 2009: location, lesion size, lack of concern.
Melanoma in situ in a private practice setting 2005 through 2009: location, lesion size, lack of concern.
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DOI：
10.1016/j.jaad.2011.11.949
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发表时间：
2012-09
影响因子：
13.8
通讯作者：
Perry, Lindall A.
中科院分区：
文献类型：
--
作者：
Stricklin, Sherea M.;Stoecker, William V.;Malters, Joseph M.;Drugge, Rhett;Oliviero, Margaret;Rabinovitz, Harold S.;Perry, Lindall A.
研究表明，原位黑色素瘤（MIS）的发病率正在显著增加。本研究分析了在美国私人皮肤科实践中观察到的MIS病例的选定临床和人口统计学特征。本研究收集了2005年1月至2009年12月美国4家私人皮肤科诊所的257例MIS病例，记录了年龄、性别、解剖位置、病变大小、患者报告的病变变化和对病变的关注。记录了同一时期侵袭性黑色素瘤的病例总数。收集的数据显示，MIS的发生率较高，在老年患者，特别是男性的阳光照射区域。MIS检测时患者的中位年龄为69岁。MIS最常见的部位是头颈部。在研究期间，收集的MIS病例数量超过浸润性恶性黑色素瘤（MM）病例数量，观察到的比例为1.37：1。回顾性收集了136例患者的病变大小、位置、性别和年龄数据。对于这些患者，未收集患者报告的病变变化和对病变的担忧。患者通常不同意进行全身检查，因此，MIS病变可能在双层覆盖区域被遗漏。仔细观察日光暴露部位（包括头皮、躯干和足部）的色素性病变，即使病变< 4mm，也有助于MIS的早期诊断。由于只有30.4%的男性和50%的女性担心这些病变，它仍然是福尔斯皮肤科医生发现MIS。
Studies have shown that the incidence of melanoma in situ (MIS) is increasing significantly. This study analyzes selected clinical and demographic characteristics of MIS cases observed in private dermatology practices in the US. This study collected 257 MIS cases from 4 private dermatology practices in the US from January 2005 through December 2009, recording age, gender, anatomic location, lesion size, patient-reported change in lesion and concern about lesion. Case totals for invasive melanoma during the same period were recorded. The data collected showed a higher incidence of MIS in sun-exposed areas of older patients, especially males. The median age of patients at the time of MIS detection was 69. The most common site for MIS was the head-neck region. The number of MIS cases collected exceeded the number of invasive malignant melanoma (MM) cases during the study period, with an observed ratio of 1.37:1. For 136 patients, data were collected retrospectively for lesion size, location, gender, and age. For these patients, patient-reported change in lesion and concern about lesion were not collected. Patients often did not consent to a full body examination, therefore, it is possible that MIS lesions may have been missed in double-clothed areas. Careful attention to pigmented lesions, even lesions < 4mm, on sun-exposed areas, including scalp, trunk, and feet, will facilitate earlier diagnosis of MIS. As only 30.4% of males and 50% of females had concern about these lesions, it still falls to the dermatologist to discover MIS.
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影响因子：
254.7
作者：
Jemal, Ahmedin;Siegel, Rebecca;Thun, Michael J.
通讯作者：
Thun, Michael J.
影响因子：
10.3
作者：
Carli, P;De Giorgi, V;Giannotti, B
通讯作者：
Giannotti, B
影响因子：
2.2
作者：
Merrill, Ray Martell
通讯作者：
Merrill, Ray Martell
DOI：
10.1111/j.1468-3083.2011.04015.x
发表时间：
2012-02-01
影响因子：
9.2
作者：
Rosina, P.;Tessari, G.;Girolomoni, G.
通讯作者：
Girolomoni, G.
影响因子：
--
作者：
Robinson, JK
通讯作者：
Robinson, JK