P50, N100, and P200 sensory gating: relationships with behavioral inhibition, attention, and working memory.

P50, N100, and P200 sensory gating: relationships with behavioral inhibition, attention, and working memory.
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DOI:
10.1111/j.1469-8986.2009.00845.x
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发表时间:
2009-09
期刊:
影响因子:
3.7
通讯作者:
Swann AC
Swann AC
中科院分区:
心理学3区
文献类型:
--
作者:
Lijffijt M;Lane SD;Meier SL;Boutros NN;Burroughs S;Steinberg JL;Moeller FG;Swann AC

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P50、N100和P200听觉感觉门控可以反映保护高阶认知功能的机制,提示感觉门控和认知之间的关系。这一假设在56名健康成年人中进行了检验,他们接受了配对点击范式和两种连续操作测试(立即/延迟记忆任务,IMT/DMT)的改编。在DMT上,较强的P50门控与较少的委托错误和延长的反应时间相关。在DMT上,较强的N100和P200门控与较好的区分性相关。最后,P200潜伏期的延长与IMT上更好的辨别能力有关。这些发现表明,P50、N100和P200门控可能通过影响反应偏差、行为抑制、工作记忆或注意力来保护认知。
P50, N100, and P200 auditory sensory gating could reflect mechanisms involved in protecting higher-order cognitive functions, suggesting relationships between sensory gating and cognition. This hypothesis was tested in 56 healthy adults who were administered the paired-click paradigm and two adaptations of the continuous performance test (Immediate/Delayed Memory Task, IMT/DMT). Stronger P50 gating correlated with fewer commission errors and prolonged reaction times on the DMT. Stronger N100 and P200 gating correlated with better discriminability on the DMT. Finally, prolonged P200 latency related to better discriminability on the IMT. These findings suggest that P50, N100, and P200 gating could be involved in protecting cognition by affecting response bias, behavioral inhibition, working memory, or attention.
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发表时间: 2004-03-01
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