Toward imaging the body at 10.5 tesla.

Toward imaging the body at 10.5 tesla.
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DOI:
10.1002/mrm.26487
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发表时间:
2017-01
影响因子:
3.3
通讯作者:
Metzger, Gregory J.
Metzger, Gregory J.
中科院分区:
医学3区
文献类型:
--
作者:
Erturk, M. Arcan;Wu, Xiaoping;Eryaman, Yigitcan;Van de Moortele, Pierre-Francois;Auerbach, Edward J.;Lagore, Russell L.;DelaBarre, Lance;Vaughan, J. Thomas;Ugurbil, Kamil;Adriany, Gregor;Metzger, Gregory J.

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通过评价类似配置的偶极天线阵列的发射/接收性能,探索在10.5T与7.0T下进行身体成像的潜力。采用数值模拟的方法,设计并评估了用于10.5T人体成像的分数偶极天线单元。研究了前列腺、肾脏和心脏内天线阵列的发射性能,并与使用纯相位RF匀场和多辐脉冲的7.0T下的发射性能进行了比较。还进行了信噪比(SNR)比较。构建了一个10通道天线阵列,用于在10.5T下对猪的腹部进行成像。在两种场强下,通过体模研究对数值方法进行了验证。在仅相位匀场的靶器官内观察到类似的功率效率,但在10.5T时RF非均匀性显著更高。与7.0T相比,轮辐式射频脉冲允许类似的发射性能,伴随局部SAR增加25-90%。在10.5T下,靶解剖结构内的相对SNR增益计算为>2倍,在体模中测量到2.2倍SNR增益。梯度回波和快速自旋回波成像证明了使用所设计的阵列在10.5T下进行身体成像的可行性。虽然使用具有10.5T静态匀场的偶极天线阵列可以实现相当的功率效率,但越来越多的RF非均匀性强调了对高效、稳健和安全的并行传输方法的需求。
To explore the potential of performing body imaging at 10.5T compared to 7.0T through evaluating the transmit/receive performance of similarly configured dipole antenna arrays. Fractionated dipole antenna elements for 10.5T body imaging were designed and evaluated using numerical simulations. Transmit performance of antenna arrays inside the prostate, kidneys and heart were investigated and compared to those at 7.0T using both phase-only RF shimming and multi-spoke pulses. Signal-to-noise ratio (SNR) comparisons were also performed. A 10-channel antenna array was constructed to image the abdomen of a swine at 10.5T. Numerical methods were validated with phantom studies at both field strengths. Similar power efficiencies were observed inside target organs with phase-only shimming, but RF non-uniformity was significantly higher at 10.5T. Spokes RF pulses allowed similar transmit performance with accompanying local SAR increases of 25–90% compared to 7.0T. Relative SNR gains inside the target anatomies were calculated to be >2-fold higher at 10.5T, and 2.2-fold SNR gain was measured in a phantom. Gradient echo and fast spin echo imaging demonstrated the feasibility of body imaging at 10.5T with the designed array. While comparable power efficiencies can be achieved using dipole antenna arrays with static shimming at 10.5T; increasing RF non-uniformities underscore the need for efficient, robust and safe parallel transmission methods.
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