Free-Space Excitation of Optofluidic Devices for Pattern-Based Single Particle Detection.
Free-Space Excitation of Optofluidic Devices for Pattern-Based Single Particle Detection.
复制标题
DOI：
10.1109/lpt.2021.3069673
复制
发表时间：
2021-08-15
期刊：
影响因子：
--
通讯作者：
Schmidt H
中科院分区：
文献类型：
--
作者：
Amin MN;Ganjalizadeh V;Hamblin M;Hawkins AR;Schmidt H
Optofluidic sensors have enabled single molecule sensing using planar, waveguide dependent multi-spot fluorescence excitation. Here, we demonstrate a new approach to single-particle fluorescence sensing using free-space, top-down illumination of liquid-core antiresonant reflecting optical waveguide (ARROW) devices using two different multi-spot excitation techniques. First, the liquid core ARROW waveguide is excited with a focused beam through a slit pattern milled into an opaque aluminum film, showing comparable performance for single bead fluorescence detection as in-plane, multi-mode interference waveguide based excitation. The second top-down illumination technique images the spot pattern from a Y-splitter SiO2 waveguide chip directly onto the detection device for efficient power utilization and circumventing the need for an opaque cover, producing a further 2.7x improvement in signal-to-noise ratio. The two top-down approaches open up new possibilities for chip-based optical particle sensing with relaxed alignment tolerances.
登录
查看更多内容
影响因子：
4.6
作者：
Ozcelik D;Jain A;Stambaugh A;Stott MA;Parks JW;Hawkins A;Schmidt H
通讯作者：
Schmidt H
DOI：
10.1109/jstqe.2015.2503321
发表时间：
2016-07-01
影响因子：
4.9
作者：
Ozcelik, Damla;Stott, Matthew A.;Schmidt, Holger
通讯作者：
Schmidt, Holger
DOI：
10.1073/pnas.1511921112
发表时间：
2015-10-20
影响因子：
11.1
作者：
Ozcelik, Damla;Parks, Joshua W.;Schmidt, Holger
通讯作者：
Schmidt, Holger
DOI：
10.1109/lpt.2017.2686354
发表时间：
2017-05-15
期刊：
IEEE photonics technology letters : a publication of the IEEE Laser and Electro-optics Society
影响因子：
--
作者：
Wall T;Hammon S;Hamilton E;Zacheu G;Orfila M;Schmidt H;Hawkins AR
通讯作者：
Hawkins AR
影响因子：
4.6
作者：
Marchetti R;Lacava C;Khokhar A;Chen X;Cristiani I;Richardson DJ;Reed GT;Petropoulos P;Minzioni P
通讯作者：
Minzioni P