Ultrasound elastography using a regularized modified error in constitutive equations (MECE) approach: a comprehensive phantom study.

Ultrasound elastography using a regularized modified error in constitutive equations (MECE) approach: a comprehensive phantom study.
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DOI:
10.1088/1361-6560/abbf97
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发表时间:
2020-11-24
影响因子:
3.5
通讯作者:
Fatemi M
Fatemi M
中科院分区:
工程技术2区
文献类型:
--
作者:
Ghavami S;Babaniyi O;Adabi S;Rosen D;Alizad A;Aquino W;Fatemi M

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瞬态弹性成像中的许多当前技术,例如剪切波弹性成像(SWE),假设在无限介质中传播的主导平面剪切波。然而,在体内的真实的场景中,这种基本假设很容易被违反,导致图像伪影和重建误差。不受平面剪切波假设约束的其他方法,例如基于偏微分方程的解,可以潜在地克服传统SWE的缺点。本文的主要目的是证明在重建不同的仿组织体模的弹性模量的总变分正则化(MECE+TV)的本构方程制定的修改后的误差比SWE的优势。实验进行了幻影与良好定义的形状的夹杂物,以研究与实际应用有关的特定功能的重建。我们比较了MECE+TV和SWE在定量指标方面的性能,以估计重建精度、夹杂物形状恢复、边缘保留和边缘锐度、夹杂物尺寸表示以及剪切弹性和对比度精度。结果表明,MECE+TV方法优于基于这些指标的SWE。它的结论是,随着进一步的发展,所提出的方法可以提供弹性成像重建是上级SWE在临床应用中。
Many of the current techniques in transient elastography, such as shear wave elastography (SWE) assume a dominant planar shear wave propagating in an infinite medium. This underlying assumption, however, can be easily violated in real scenarios in vivo, leading to image artifacts and reconstruction errors. Other approaches that are not bound to planar shear wave assumption, such solutions based on the partial differential equation, can potentially overcome the shortcomings of the conventional SWE. The main objective of this paper is to demonstrate the advantages of the modified error in constitutive equations formulation with total variation regularization (MECE+TV) over SWE in reconstructing the elastic moduli of different tissue-mimicking phantoms. Experiments were conducted on phantoms with inclusions of well-defined shapes to study the reconstruction of specific features relevant to practical applications. We compared the performances of MECE+TV and SWE in terms of quantitative metrics to estimate reconstruction accuracy, inclusion shape recovery, edge preservation and edge sharpness, inclusion size representation, and shear elasticity and contrast accuracies. The results indicate that the MECE+TV approach outperforms SWE based on several of these metrics. It is concluded that, with further development, the proposed method may offer elastography reconstructions that are superior to SWE in clinical applications.
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