Multimodality cardiovascular molecular imaging technology.

Multimodality cardiovascular molecular imaging technology.
复制标题

DOI:
10.2967/jnumed.109.068155
复制
发表时间:
2010-05-01
期刊:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine
影响因子:
--
通讯作者:
Garcia EV
Garcia EV
中科院分区:
其他
文献类型:
--
作者:
O'Donnell M;McVeigh ER;Strauss HW;Tanaka A;Bouma BE;Tearney GJ;Guttman MA;Garcia EV

文献摘要

参考文献

被引文献

相似文献

心血管分子影像学是一门新兴学科,它整合了功能成像和分子探针的科学进展,以提高我们对心血管系统分子基础的理解。这些进展是由动物(通常是小动物)分子过程的体内成像推动的,并且正在迅速走向临床应用。分子影像学有可能彻底改变心血管疾病的诊断和治疗。所有分子成像系统的2个关键组件是分子造影剂和提供这些造影剂在体内的空间和时间定位的成像系统。它们必须提供具有适当灵敏度和特异性的图像,以推动临床应用。随着分子造影剂研究的成熟以及高灵敏度和特异性探针的开发,这些系统将提供转化为临床工具所需的成像技术。这就是分子医学的前景。
Cardiovascular molecular imaging is a new discipline that integrates scientific advances in both functional imaging and molecular probes to improve our understanding of the molecular basis of the cardiovascular system. These advances are driven by in vivo imaging of molecular processes in animals, usually small animals, and are rapidly moving toward clinical applications. Molecular imaging has the potential to revolutionize the diagnosis and treatment of cardiovascular disease. The 2 key components of all molecular imaging systems are the molecular contrast agents and the imaging system providing spatial and temporal localization of these agents within the body. They must deliver images with the appropriate sensitivity and specificity to drive clinical applications. As work in molecular contrast agents matures and highly sensitive and specific probes are developed, these systems will provide the imaging technologies required for translation into clinical tools. This is the promise of molecular medicine.
DOI: 10.1016/s0735-1097(83)80100-4
发表时间: 1983-01-01
影响因子: 24
作者:
BROWN, KA;BOUCHER, CA;POHOST, GM
通讯作者: POHOST, GM
DOI: 10.1161/01.cir.0000095790.28368.f9
发表时间: 2003-12-09
期刊: CIRCULATION
影响因子: 37.8
作者:
Dick, AJ;Guttman, MA;Lederman, RJ
通讯作者: Lederman, RJ
DOI: 10.1161/01.cir.0000080326.15367.0c
发表时间: 2003-07-22
期刊: CIRCULATION
影响因子: 37.8
作者:
Ellegala, DB;Poi, HL;Lindner, JR
通讯作者: Lindner, JR
DOI: 10.1081/jcmr-120016382
发表时间: 2002-01-01
影响因子: 6.4
作者:
Guttman, MA;Lederman, RJ;McVeigh, ER
通讯作者: McVeigh, ER
DOI: 10.1161/01.cir.0000084537.66419.7a
发表时间: 2003-08-26
期刊: CIRCULATION
影响因子: 37.8
作者:
Hill, JM;Dick, AJ;Lederman, RJ
通讯作者: Lederman, RJ