The role of oxidative stress in the pathogenesis of asthma.
The role of oxidative stress in the pathogenesis of asthma.
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DOI:
10.4168/aair.2010.2.3.183
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发表时间:
2010-07
期刊:
影响因子:
--
通讯作者:
Moon HB
中科院分区:
文献类型:
--
作者:
Cho YS;Moon HB
Oxidative stress plays a critical role in the pathogenesis of asthma. To effectively control oxidative stress in asthmatics, it is important to investigate the precise intracellular mechanism by which the development of immunity, rather than immune tolerance and progression of airway inflammation, is induced. In this article, we suggest that protein tyrosine phosphatases, as intracellular negative regulators, and intracellular antioxidant enzymes such as peroxiredoxins can be regulated by oxidative stress during intracellular signaling.
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