Higher education is an age-independent predictor of white matter integrity and cognitive control in late adolescence.
Higher education is an age-independent predictor of white matter integrity and cognitive control in late adolescence.
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DOI：
10.1111/desc.12077
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发表时间：
2013-09
影响因子：
3.7
通讯作者：
Brickman AM
中科院分区：
文献类型：
--
作者：
Noble KG;Korgaonkar MS;Grieve SM;Brickman AM
社会经济地位是认知发展和学业成就的重要预测因素。在与年龄相关的认知和神经发育正在进行的时期，青春期晚期提供了一个独特的机会来研究社会经济地位的实现（以教育年数的形式）与认知和神经发育之间的关系。在青春期后期，有可能消除年龄和教育对这些过程发展的影响。在这里，我们评估了高等教育程度与认知控制任务表现的关系程度，控制了年龄。然后，我们使用扩散张量成像（DTI）来评估白质微观结构可能介导这种关系的程度。当年龄共变时，受教育程度与上纵束和扣带束的分数各向异性（FA）显著相关。此外，当年龄共变时，这些区域的FA与认知控制有关。最后，中介分析显示，受教育程度和认知控制之间的年龄独立关联完全由FA解释。钩状束，一个与认知控制无关的晚髓鞘控制区，没有介导这种效应。
Socioeconomic status is an important predictor of cognitive development and academic achievement. Late adolescence provides a unique opportunity to study how the attainment of socioeconomic status (in the form of years of education) relates to cognitive and neural development, during a time when age-related cognitive and neural development is ongoing. During late adolescence it is possible to disambiguate age- and education-related effects on the development of these processes. Here we assessed the degree to which higher educational attainment was related to performance on a cognitive control task, controlling for age. We then used diffusion tensor imaging (DTI) to assess the degree to which white matter microstructure might mediate this relationship. When covarying age, significant associations were found between educational attainment and fractional anisotropy (FA) in the superior longitudinal fasciculus (SLF) and cingulum bundle (CB). Further, when covarying age, FA in these regions was associated with cognitive control. Finally, mediation analyses revealed that the age-independent association between educational attainment and cognitive control was completely accounted for by FA in these regions. The uncinate fasciculus, a late-myelinated control region not implicated in cognitive control, did not mediate this effect.
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影响因子：
7.6
作者：
BARON, RM;KENNY, DA
通讯作者：
KENNY, DA
影响因子：
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