Retroviruses and Their Role in Cancer
Retroviruses and Their Role in Cancer
复制标题
逆转录病毒及其在癌症中的作用
DOI:
10.1007/978-1-4899-1730-0_7
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发表时间:
1994
影响因子:
3.2
通讯作者:
H. Fan
中科院分区:
文献类型:
--
作者:
H. Fan
Historically, retroviruses were first isolated and studied because they efficiently cause tumors in experimental and domestic animals (Rous, 1911; Ellerman and Bang, 1908). Work was particularly intense during the 1970s, under the “War on Cancer” and the Special Virus Cancer Program. Important discoveries from re-trovirology such as oncogenes and proto-oncogenes (Bishop, 1987) have had profound implications for understanding tumorigenesis, including for spontaneous human tumors. Retroviruses remain some of the best model systems for studying carcinogenesis in the whole organism, since they induce tumors with extremely high efficiency. The focus of this chapter will be retroviral carcinogenesis in small animal models. Major attention will be paid to nonacute retroviruses, since they induce disease through multiple steps, with analogies to non-virus-induced cancer as well.
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DOI:
10.1099/0022-1317-66-1-83
发表时间:
1985
期刊:
The Journal of general virology
影响因子:
--
作者:
Bondurant,MC;Koury,MJ;Krantz,SB
通讯作者:
Krantz,SB
DOI:
10.1126/science.6344220
发表时间:
1983
期刊:
Science (New York, N.Y.)
影响因子:
--
作者:
Rasheed,S;Norman,GL;Heidecker,G
通讯作者:
Heidecker,G
影响因子:
3.7
作者:
Weinhold,KJ;Hüper,G;Matthews,TJ;Fischinger,PJ;Ihle,JN;Schwarz,H;Thiel,HJ;Schäfer,W;Bolognesi,DP
通讯作者:
Bolognesi,DP
DOI:
10.1126/science.1310360
发表时间:
1992
期刊:
Science (New York, N.Y.)
影响因子:
--
作者:
Coffin,JM
通讯作者:
Coffin,JM
影响因子:
56.9
作者:
BISHOP, JM
通讯作者:
BISHOP, JM