Shear wave dispersion measures liver steatosis.
Shear wave dispersion measures liver steatosis.
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DOI:
10.1016/j.ultrasmedbio.2011.10.019
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发表时间:
2012-02
影响因子:
2.9
通讯作者:
Parker, Kevin J.
中科院分区:
文献类型:
--
作者:
Barry, Christopher T.;Mills, Bradley;Hah, Zaegyoo;Mooney, Robert A.;Ryan, Charlotte K.;Rubens, Deborah J.;Parker, Kevin J.
关键词:
Crawling waves, which are interfering shear wave patterns, can be generated in liver tissue over a range of frequencies. Some important biomechanical properties of the liver can be determined by imaging the crawling waves using Doppler techniques and analyzing the patterns. We report that the dispersion of shear wave velocity and attenuation, that is, the frequency dependence of these parameters, are strongly correlated with the degree of steatosis in a mouse liver model, ex vivo. The results demonstrate the possibility of assessing liver steatosis using noninvasive imaging methods that are compatible with color Doppler scanners and, furthermore, suggest that liver steatosis can be separated from fibrosis by assessing the dispersion or frequency dependence of shear wave propagations.
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影响因子:
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通讯作者:
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DOI:
10.1093/qjmed/hcp158
发表时间:
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期刊:
QJM : monthly journal of the Association of Physicians
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