The biology of ovarian cancer: new opportunities for translation.
The biology of ovarian cancer: new opportunities for translation.
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DOI:
10.1038/nrc2644
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发表时间:
2009-06
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影响因子:
--
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Over the past two decades, the 5-year survival for ovarian cancer patients has substantially improved owing to more effective surgery and treatment with empirically optimized combinations of cytotoxic drugs, but the overall cure rate remains approximately 30%. Many investigators think that further empirical trials using combinations of conventional agents are likely to produce only modest incremental improvements in outcome. Given the heterogeneity of this disease, increases in long-term survival might be achieved by translating recent insights at the molecular and cellular levels to personalize individual strategies for treatment and to optimize early detection.
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影响因子:
45.3
作者:
CANNISTRA, SA;ABUJAWDEH, G;OTTENSMEIER, C
通讯作者:
OTTENSMEIER, C
DOI:
10.1016/0002-9378(92)91697-9
发表时间:
1992-02-01
影响因子:
9.8
作者:
BERCHUCK, A;RODRIGUEZ, G;BAST, RC
通讯作者:
BAST, RC
影响因子:
45.3
作者:
Bookman, MA;Darcy, KM;Horowitz, IR
通讯作者:
Horowitz, IR
影响因子:
4.8
作者:
Barbolina, Maria V.;Adley, Brian P.;Stack, M. Sharon
通讯作者:
Stack, M. Sharon
DOI:
10.4161/cc.8.1.7533
发表时间:
2009-01-01
期刊:
Cell cycle (Georgetown, Tex.)
影响因子:
--
作者:
Alvero AB;Chen R;Fu HH;Montagna M;Schwartz PE;Rutherford T;Silasi DA;Steffensen KD;Waldstrom M;Visintin I;Mor G
通讯作者:
Mor G