Cerebral functional imaging using near-infrared spectroscopy during repeated performances of motor rehabilitation tasks tested on healthy subjects.
Cerebral functional imaging using near-infrared spectroscopy during repeated performances of motor rehabilitation tasks tested on healthy subjects.
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DOI：
10.3389/fnhum.2014.00292
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发表时间：
2014
影响因子：
2.9
通讯作者：
Nishijo H
中科院分区：
文献类型：
--
作者：
Ishikuro K;Urakawa S;Takamoto K;Ishikawa A;Ono T;Nishijo H
为了探讨额叶和感觉运动皮层与运动学习之间的关系，使用功能性近红外光谱（NIRS）技术记录额叶和感觉运动皮层的血流动力学反应，同时健康受试者进行康复医学中使用的运动学习任务。全头近红外光谱记录表明，前背内侧前额叶皮层（aDMPFC）的反应潜伏期短于其他额叶和顶叶区域。此外，在8次重复试验中，aDMPFC中血流动力学反应的增量率与其他区域的血流动力学反应的增量率显著相关，并且与8次重复试验中任务表现的改善率显著相关。在第二个实验中，为了分离头皮和脑源性血液动力学反应，使用多距离探针布置从aDMPFC上方的头部记录血液动力学反应。将六个探针（单个源探针和5个检测器）线性放置成与每个相邻探针相距6mm。使用独立成分分析的血流动力学信号从5个源探测器对，我们分离头皮和脑衍生的成分的血流动力学反应。在8项试验中，经aDMPFC校正的头皮源性反应的血流动力学反应显著增加，并与任务表现相关。在第三个实验中，受试者被要求在任务前进行相同的任务，有和没有aDMPFC的经颅直流电刺激（tDCS）。tDCS显著改善了任务性能。这些结果表明，aDMPFC是至关重要的重复运动学习的性能改善。
To investigate the relationship between the frontal and sensorimotor cortices and motor learning, hemodynamic responses were recorded from the frontal and sensorimotor cortices using functional near infrared spectroscopy (NIRS) while healthy subjects performed motor learning tasks used in rehabilitation medicine. Whole-head NIRS recordings indicated that response latencies in the anterior dorsomedial prefrontal cortex (aDMPFC) were shorter than in other frontal and parietal areas. Furthermore, the increment rate of the hemodynamic responses in the aDMPFC across the eight repeated trials significantly correlated with those in the other areas, as well as with the improvement rate of task performance across the 8 repeated trials. In the second experiment, to dissociate scalp- and brain-derived hemodynamic responses, hemodynamic responses were recorded from the head over the aDMPFC using a multi-distance probe arrangement. Six probes (a single source probe and 5 detectors) were linearly placed 6 mm apart from each of the neighboring probes. Using independent component analyses of hemodynamic signals from the 5 source-detector pairs, we dissociated scalp- and brain-derived components of the hemodynamic responses. Hemodynamic responses corrected for scalp-derived responses over the aDMPFC significantly increased across the 8 trials and correlated with task performance. In the third experiment, subjects were required to perform the same task with and without transcranial direct current stimulation (tDCS) of the aDMPFC before the task. The tDCS significantly improved task performance. These results indicate that the aDMPFC is crucial for improved performance in repetitive motor learning.
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影响因子：
3.4
作者：
Boros, Klara;Poreisz, Csaba;Nitsche, Michael A.
通讯作者：
Nitsche, Michael A.
影响因子：
7.7
作者：
Brunoni, Andre Russowsky;Nitsche, Michael A.;Bolognini, Nadia;Bikson, Marom;Wagner, Tim;Merabet, Lotfi;Edwards, Dylan J.;Valero-Cabre, Antoni;Rotenberg, Alexander;Pascual-Leone, Alvaro;Ferrucci, Roberta;Priori, Alberto;Boggio, Paulo Sergio;Fregni, Felipe
通讯作者：
Fregni, Felipe
DOI：
10.1073/pnas.83.4.1140
发表时间：
1986-02-01
影响因子：
11.1
作者：
FOX, PT;RAICHLE, ME
通讯作者：
RAICHLE, ME
DOI：
10.1016/s0003-9993(96)90262-2
发表时间：
1996-08-01
影响因子：
4.3
作者：
Hanlon, RE
通讯作者：
Hanlon, RE
影响因子：
--
作者：
Halsband, Ulrike;Lange, Regine K.
通讯作者：
Lange, Regine K.