Sleep disturbance and psychological distress are associated with functional dyspepsia based on Rome III criteria.
Sleep disturbance and psychological distress are associated with functional dyspepsia based on Rome III criteria.
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DOI：
10.1186/s12888-018-1720-0
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发表时间：
2018-05-18
期刊：
影响因子：
4.4
通讯作者：
Lin L
中科院分区：
文献类型：
--
作者：
Li Y;Gong Y;Li Y;He D;Wu Y;Wang H;Cong X;Wei M;Lin L
功能性消化不良(FD)被认为是一种生物心理社会障碍。心理社会因素在FD发病机制中的作用尚不清楚。这项研究评估了FD患者的睡眠质量和情绪症状，评估了FD严重程度、睡眠障碍和心理症状之间的关系。115名具有典型FD症状的成人患者与61名健康志愿者一起被纳入研究。采用罗马III标准评定FD症状，匹兹堡睡眠质量指数(PSQI)评定睡眠障碍，症状自评量表(SCL-90R)评定抑郁、焦虑等心理症状。FD患者的PSQI评分和SCL-90R的9个症状维度均显著高于对照组。多因素Logistic回归分析显示，低BMI、低文化程度和睡眠障碍与FD和FD亚组独立相关。敌对和恐怖是FD的独立危险因素。进一步分析表明，敌意是FD两个亚组的独立危险因素，躯体化和其他精神症状是上腹痛综合征的独立危险因素。我们发现FD与睡眠障碍和精神病理因素有关。这些发现表明，实施睡眠和/或心理治疗可能有助于减轻FD症状。
Functional dyspepsia (FD) is considered a bio-psychosocial disorder. The role of psychosocial factors in FD pathogenesis remains unclear. This study evaluated sleep quality and mood symptoms in patients with FD, assessing the associations of FD severity, disordered sleep, and psychological symptoms. One-hundred-and-fifteen adult patients with typical FD symptoms were enrolled alongside 61 healthy volunteers. Rome III criteria were used to evaluate FD symptoms; sleep disorder was assessed with the Pittsburgh Sleep Quality Index (PSQI), and Symptom Checklist-90-Revised (SCL-90R) was utilized to determine the status of depression, anxiety and other psychological symptoms. PSQI scores and nine symptomatic dimensions of SCL-90R were significantly higher in FD patients than in controls. Multiple logistic regression indicated that lower BMI, lower level of education, and sleep disturbance were independently associated with FD and FD subgroups. Hostility and phobic anxiety were independent risk factors for FD. Further analysis showed that hostility was an independent risk factor for both FD subgroups, and somatization and additional psychiatric symptoms for epigastric pain syndrome. We found that FD was associated with sleep disorder and psychopathological factors. These findings suggest that implementing sleeping and/or psychological therapies may help reduce FD symptoms.
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影响因子：
3.4
作者：
Miwa H;Ghoshal UC;Gonlachanvit S;Gwee KA;Ang TL;Chang FY;Fock KM;Hongo M;Hou X;Kachintorn U;Ke M;Lai KH;Lee KJ;Lu CL;Mahadeva S;Miura S;Park H;Rhee PL;Sugano K;Vilaichone RK;Wong BC;Bak YT
通讯作者：
Bak YT
影响因子：
12.6
作者：
Tack, Jan;Ly, Huynh Giao;Van Oudenhove, Lukas
通讯作者：
Van Oudenhove, Lukas
影响因子：
9.8
作者：
Mahadeva, Sanjiv;Yadav, Hematram;Goh, Khean-Lee
通讯作者：
Goh, Khean-Lee
影响因子：
12.6
作者：
Jones, Michael P.;Tack, Jan;Talley, Nicholas J.
通讯作者：
Talley, Nicholas J.
影响因子：
3.5
作者：
Cremonini, F.;Camilleri, M.;Zinsmeister, A. R.;Herrick, L. M.;Beebe, T.;Talley, N. J.
通讯作者：
Talley, N. J.