Optical 3-D Metric Measurements of Local Vocal Fold Deformation Characteristics in an In Vitro Setup
Optical 3-D Metric Measurements of Local Vocal Fold Deformation Characteristics in an In Vitro Setup
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体外设置中局部声带变形特征的光学 3D 公制测量
DOI：
10.1109/tbme.2011.2130525
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发表时间：
2011
影响因子：
4.6
通讯作者：
M. Döllinger
中科院分区：
文献类型：
--
作者：
C. B. Hüttner;A. Sutor;G. Luegmair;S. Rupitsch;R. Lerch;M. Döllinger
了解声带动力学是治疗嗓音疾病的重要组成部分，因为它是适当药物治疗的先决条件。存在各种物理和数值模型用于模拟目的，所有这些都依赖于简化的材料参数。为了改进当前的方法，需要真实组织行为的数据，即，在自然环境中，必须在模型开发中考虑。提出了一种体外设置结合光学方法进行拉伸试验，用于精确、局部和测量不同表面点的3-D测量。与以前的三维重建方法相比，精度提高了10倍。对10只猪声带测量垂直施加的力与产生的变形。观察了声带边缘沿着3个不同部位粘膜的变形特征及粘膜-肌肉双层结构。弹簧刚度率用指数函数表示。对于相等的偏转，测量到MM从后向前的弹簧刚度增加。对于单独的粘膜，弹簧率从后部到中部降低，随后再次增加。MM层呈现比粘膜更硬的变形行为。对于大于1.5 mm的变形，MM的弹簧率是粘膜的两倍多。研究结果表明，在声带模型的改进中，同时考虑多层和局部差异的重要性。
Understanding vocal fold dynamics presents an essential part in treating voice disorders as it is the prerequisite to appropriate medical therapy. Various physical and numerical models exist for simulation purposes, all relying on simplified material parameters. To improve current approaches, data of realistic tissue behavior, i.e., in natural surroundings, have to be considered in model development. An in vitro setup was proposed for tensile tests combined with an optical method for precise, local and metrical 3-D measurements of distinctive surface points. Compared to previous 3-D reconstruction methods, the accuracy was improved tenfold. Vertically applied forces versus resulting deformation were measured for ten porcine vocal folds. Deformation characteristics of mucosa and the two-layer structure of mucosa and muscle (MM) were investigated at three distinctive locations along the vocal fold edge. The spring rates were represented by an exponential function. For equal deflections, an increasing spring rate from posterior to anterior for MM was measured. For solely mucosa, the spring rate decreased from the posterior to the middle and subsequently increased again. The MM-layer presented a stiffer deformation behavior than mucosa. For deformations higher than 1.5 mm, the spring rates for MM were more than twice as high as for mucosa. The investigations display the importance of considering both multilayers and local differences for the improvement of vocal fold models.
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使用空气脉冲刺激测量伤痕累累的兔子声带的弹性
影响因子：
1.1
作者：
S. Hertegård;H. Larsson;S. R. Nagubothu;Anna Tolf;Bengt Svensson
通讯作者：
Bengt Svensson
DOI：
10.1016/j.cma.2009.06.009
发表时间：
2009-01-01
影响因子：
7.2
作者：
Link, G.;Kaltenbacher, M.;Doellinger, M.
通讯作者：
Doellinger, M.
DOI：
10.1121/1.3543988
发表时间：
2011
期刊：
The Journal of the Acoustical Society of America
影响因子：
--
作者：
Schmidt,Bastian;Stingl,Michael;Leugering,Gunter;Berry,DavidA;Dollinger,Michael
通讯作者：
Dollinger,Michael
影响因子：
1
作者：
Hess, Markus M.;Mueller, Frank;Goodyer, Eric
通讯作者：
Goodyer, Eric
影响因子：
10.6
作者：
Lohscheller, Joerg;Eysholdt, Ulrich;Doellinger, Michael
通讯作者：
Doellinger, Michael