Elasticity measurements in scarred rabbit vocal folds using air pulse stimulation

Elasticity measurements in scarred rabbit vocal folds using air pulse stimulation
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使用空气脉冲刺激测量伤痕累累的兔子声带的弹性

DOI:
10.3109/14015430902913527
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发表时间:
2009
影响因子:
1.1
通讯作者:
Bengt Svensson
Bengt Svensson
中科院分区:
医学4区
文献类型:
--
作者:
S. Hertegård;H. Larsson;S. R. Nagubothu;Anna Tolf;Bengt Svensson

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摘要 本研究旨在比较通过短空气脉冲刺激粘膜进行非侵入性分析的新方法的声带弹性数据。粘膜偏转的深度是通过特殊算法用激光脉冲测量的。处死后立即测量十只有疤痕的新西兰兔声带和四只正常兔声带。将弹性数据与病理学家分析的疤痕声带的组织学切片进行比较。结果显示,与轻微损伤的样本相比,疤痕较多的声带弹性值明显较低(硬度较高)(P=0.03)。结论是,空气脉冲刺激方法是一种有前途的非侵入性量化声带疤痕的工具。
Abstract This study aimed to compare vocal fold elasticity data from a new method for non-invasive analysis by stimulations of the mucosa with short air pulses. The depth of the mucosal deflections is measured with laser pulses by means of a special algorithm. Ten scarred New Zealand rabbit vocal folds and four normal rabbit folds were measured directly after sacrifice. The elastic data were compared to histological sections from the scarred vocal folds analysed by a pathologist. The results showed significantly lower elasticity (higher stiffness) values for the more scarred vocal folds as compared to samples with minor damage (P=0.03). It is concluded that the air pulse stimulation method is a promising tool for non-invasive quantification of vocal fold scarring.
DOI: 10.1016/s0892-1997(02)00078-4
发表时间: 2002-03-01
期刊: JOURNAL OF VOICE
影响因子: 2.2
作者:
Thibeault, SL;Gray, SD;Ford, CN
通讯作者: Ford, CN
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发表时间: 2001-06-01
影响因子: 3.4
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发表时间: 2009-03-01
期刊: JOURNAL OF VOICE
影响因子: 2.2
作者:
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通讯作者: Goodyer, Eric