The propagation speeds of calcium action potentials are remarkably invariant.

The propagation speeds of calcium action potentials are remarkably invariant.
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钙动作电位的传播速度显着不变。

DOI:
10.1016/s0248-4900(03)00090-x
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发表时间:
2003
影响因子:
2.7
通讯作者:
Jaffe,LionelF
Jaffe,LionelF
中科院分区:
生物学4区
文献类型:
--
作者:
Jaffe,LionelF

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本文批判性地汇编了所有已发表的已确定或推定的钙动作电位(或超快钙波)的案例,其中它们的速度是已知的并且不受细胞间延迟的限制。这 127 个案例包括来自刺胞动物、栉水母、软体动物、甲壳动物、蠕虫、棘皮动物和被囊动物直至哺乳动物大脑等系统内神经元或神经网络的数据;从Beröe、Cestum、飞蛾、螃蟹、软体动物、被囊动物、青蛙、鸡胚和海龟到哺乳动物心脏等生物体中的肌肉细胞;来自刺胞动物和被囊动物的上皮;甚至来自甲藻和食虫植物以及重组的心丝。他们揭示了 20 摄氏度时值约为 10-40 厘米/秒的限制以及其他温度下的类似限制。此外,与钠动作电位的速度不同,钙动作电位的速度与细胞直径无关,至少在大约 0.1 至 30 微米的可用范围内是如此。为什么钙动作电位具有如此固定的传播速度?也许进化使它们成为最快的钙流入波,从而避免地下中毒。
This paper critically compiles all published cases of established or putative calcium action potentials (or ultrafast calcium waves) where their speeds are known and are not limited by intercellular delays. The 127 cases include data from neurons or nerve nets within systems that range from cnidaria, ctenophores, molluscs, crustaceans, worms, echinoderms and tunicates up to mammalian brains; from muscle cells within organisms that range fromBeröe, Cestum, moths, a crab, molluscs, a tunicate, frogs, chick embryos and turtles up to mammalian hearts; from epithelia in cnidaria and tunicates; even from a dinoflagellate and an insectivorous plant as well as reconstituted heart strands. They reveal a restriction to values of about 10–40 cm/sec at 20 degrees C and comparable restrictions at other temperatures. Moreover — unlike the speeds of sodium action potentials — the speeds of calcium ones are unrelated to cell diameter, at least over the available range of about 0.1 to 30 microns. Why do calcium action potentials have such fixed propagation speeds? Perhaps evolution has driven them to be the fastest waves of calcium influx which avoid subsurface poisoning.
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