Reconstructing the evolutionary origins and phylogeography of hantaviruses.

Reconstructing the evolutionary origins and phylogeography of hantaviruses.
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DOI:
10.1016/j.tim.2014.04.008
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发表时间:
2014-08
影响因子:
15.9
通讯作者:
Yanagihara, Richard
Yanagihara, Richard
中科院分区:
生物学1区
文献类型:
--
作者:
Bennett, Shannon N.;Gu, Se Hun;Kang, Hae Ji;Arai, Satoru;Yanagihara, Richard

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长期以来,啮齿动物被认为是汉坦病毒的主要宿主。然而,随着汉他病毒在来自广泛分离的地理区域的多种物种的鼩、鼹鼠和食虫蝙蝠中的遗传上不同和遗传上不同的谱系的发现,汉他病毒宿主分布、进化和寄生地理学的复杂得多的景观正在出现。详细的系统发育分析,部分和全长基因组的基础上,以前描述的啮齿类动物传播的汉他病毒和新检测到的非啮齿类动物传播的汉他病毒,表明亚洲起源,并支持新出现的概念,即祖先的非啮齿类哺乳动物可能担任原始汉他病毒的宿主。
Rodents have long been recognized as the principal reservoirs of hantaviruses. However, with the discovery of genetically distinct and phylogenetically divergent lineages of hantaviruses in multiple species of shrews, moles, and insectivorous bats from widely separated geographic regions, a far more complex landscape of hantavirus host distribution, evolution, and phylogeography is emerging. Detailed phylogenetic analyses, based on partial and full-length genomes of previously described rodent-borne hantaviruses and newly detected non-rodent-borne hantaviruses, indicate an Asian origin and support the emerging concept that ancestral non-rodent mammals may have served as the hosts of primordial hantaviruses.
蝙蝠、食虫动物和啮齿动物携带的汉坦病毒的系统发育和起源
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