Investigation of the impact of total sleep deprivation at home on the number of intrusive memories to an analogue trauma
Investigation of the impact of total sleep deprivation at home on the number of intrusive memories to an analogue trauma
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调查在家中完全睡眠不足对模拟创伤侵入性记忆数量的影响
DOI：
10.1038/s41398-019-0403-z
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发表时间：
2019
影响因子：
6.8
通讯作者：
E. Holmes
中科院分区：
文献类型：
--
作者：
K. Porcheret;Dalena van Heugten;G. Goodwin;R. Foster;K. Wulff;E. Holmes
睡眠可以增强记忆的巩固；然而，在事件记忆可能导致精神病理学的情况下，例如创伤事件后，睡眠的这种特性可能是有害的。创伤的侵入性记忆是不由自主地浮现在脑海中的情感记忆，是创伤后应激障碍的核心特征。在一项研究中，与正常睡眠相比，在模拟创伤（创伤电影）后的第一晚，在医院环境中完全剥夺睡眠会导致侵入性记忆减少。目前的研究旨在测试这些发现的延伸：在更自然的条件下——在家中——睡眠不足。多导睡眠图记录显示在家中实现了不一致的睡眠剥夺。在睡眠不足的情况下，拍摄创伤录像后的第一天，侵入性记忆较少。第二天发现了相反的情况：在睡眠不足的情况下，侵入性记忆更多。然而，去除两名具有极值的参与者后，没有发现显着差异，并且在创伤电影拍摄后一周内报告的侵入性记忆总数也没有发现差异。研究发现，在睡眠剥夺的情况下，创伤影片的自愿记忆略有受损。总之，与我们早期在医院环境中使用完全睡眠剥夺的研究结果相比，在当前的研究中，在家中使用不一致的睡眠剥夺并不能复制减少侵入性记忆数量的结果模式。考虑到睡眠剥夺的条件（自然与医院）需要进一步检查。
Sleep enhances the consolidation of memory; however, this property of sleep may be detrimental in situations where memories of an event can lead to psychopathology, such as following a traumatic event. Intrusive memories of trauma are emotional memories that spring to mind involuntarily and are a core feature of post-traumatic stress disorder. Total sleep deprivation in a hospital setting on the first night after an analogue trauma (a trauma film) led to fewer intrusive memories compared to sleep as usual in one study. The current study aimed to test an extension of these findings: sleep deprivation under more naturalistic conditions—at home. Polysomnographic recordings show inconsistent sleep deprivation was achieved at home. Fewer intrusive memories were reported on day 1 after the trauma film in the sleep-deprived condition. On day 2 the opposite was found: more intrusive memories in the sleep-deprived condition. However, no significant differences were found with the removal of two participants with extreme values and no difference was found in the total number of intrusive memories reported in the week following the trauma film. Voluntary memory of the trauma film was found to be slightly impaired in the sleep deprivation condition. In conclusion, compared to our eariler findings using total sleep deprivation in a hospital setting, in the current study the use of inconsistent sleep deprivation at home does not replicate the pattern of results on reducing the number of intrusive memories. Considering the conditions under which sleep deprivation (naturalistic versus hospital) was achieved requires further examination.
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影响因子：
22.4
作者：
Walker, Matthew P.;van der Helm, Els
通讯作者：
van der Helm, Els
影响因子：
17.7
作者：
Mellman, TA;Bustamante, V;Nolan, B
通讯作者：
Nolan, B
影响因子：
3.3
作者：
Mellman, Thomas A.;Pigeon, Wilfred R.;Nolan, Bruce
通讯作者：
Nolan, Bruce
影响因子：
4.8
作者：
Galatzer-Levy, Isaac R.;Karstoft, Karen-Inge;Statnikov, Alexander;Shalev, Arieh Y.
通讯作者：
Shalev, Arieh Y.
昼夜节律。
DOI：
10.1016/b978-0-12-571149-4.50007-6
发表时间：
1994
期刊：
Recent progress in hormone research
影响因子：
--
作者：
Turek,FW
通讯作者：
Turek,FW