Wnt signaling and osteoporosis.
Wnt signaling and osteoporosis.
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DOI:
10.1016/j.maturitas.2014.04.013
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发表时间:
2014-07
期刊:
影响因子:
4.9
通讯作者:
Manolagas SC
中科院分区:
文献类型:
--
作者:
Manolagas SC
Major advances in understanding basic bone biology and the cellular and molecular mechanisms responsible for the development of osteoporosis, over the last 20 years, have dramatically altered the management of this disease. The purpose of this mini-review is to highlight the seminal role of Wnt signaling in bone homeostasis and disease and the emergence of novel osteoporosis therapies by targeting Wnt signaling with drugs.
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