Isolation by distance, web service.

Isolation by distance, web service.
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DOI:
10.1186/1471-2156-6-13
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发表时间:
2005-03-11
期刊:
影响因子:
2.9
通讯作者:
Kelley, ST
Kelley, ST
中科院分区:
生物学3区
文献类型:
--
作者:
Jensen, JL;Bohonak, AJ;Kelley, ST

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被称为“距离隔离”的群体遗传模式是由空间有限的基因流动造成的,是自然群体中常见的现象。然而,很少有软件程序存在估计人口之间的距离隔离的程度,他们往往不是用户友好。我们已经创建了距离隔离Web服务(IBDWS),这是一个用户友好的Web界面,用于确定距离隔离模式。使用该网站,群体遗传学家可以进行各种强大的统计测试,包括Mantel测试,减少主轴(RMA)回归分析,以及计算所有对群体之间的FST,并进行基本的汇总统计(例如,杂合性)。所有统计结果,包括Postscript格式的可发表质量的散点图,都迅速返回给用户,并可方便地下载。IBDWS群体遗传学分析软件托管在,文档可在。源代码已在Source Forge上提供,网址为。
The population genetic pattern known as "isolation by distance" results from spatially limited gene flow and is a commonly observed phenomenon in natural populations. However, few software programs exist for estimating the degree of isolation by distance among populations, and they tend not to be user-friendly. We have created Isolation by Distance Web Service (IBDWS) a user-friendly web interface for determining patterns of isolation by distance. Using this site, population geneticists can perform a variety of powerful statistical tests including Mantel tests, Reduced Major Axis (RMA) regression analysis, as well as calculate FST between all pairs of populations and perform basic summary statistics (e.g., heterozygosity). All statistical results, including publication-quality scatter plots in Postscript format, are returned rapidly to the user and can be easily downloaded. IBDWS population genetics analysis software is hosted at and documentation is available at . The source code has been made available on Source Forge at .
DOI: 10.1073/pnas.93.19.10528
发表时间: 1996-09-17
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