Contribution of both positive selection and relaxation of selective constraints to degeneration of flyability during geese domestication.
Contribution of both positive selection and relaxation of selective constraints to degeneration of flyability during geese domestication.
复制标题
正向选择和放宽选择性约束对鹅驯化过程中飞行性退化的贡献
DOI：
10.1371/journal.pone.0185328
复制
发表时间：
2017
期刊：
影响因子：
3.7
通讯作者：
Liu Y
中科院分区：
文献类型：
--
作者：
Wang Y;Hu Y;He D;Chen S;Li S;Lan D;Ren P;Lin Z;Liu Y
飞行性是现代鹅与其野生祖先最大的差异，飞行性退化是野鹅驯化成功的重要标志。鉴于家鹅的历史相对较短，强烈的人工选择被认为在飞行性能的退化中起着重要作用。然而，这一现象背后的潜在机制却很少被研究。在这项研究中，我们应用分子进化的方法来评估部分品种的家鹅，以寻找基因参与的选择压力对飞行性能退化。单倍型网络，成对固定指数（FST）值，和分子方差分析结果都清楚地说明了朗德鹅和部分中国家鹅之间的群体差异。我们还检测到COX2和COX3基因中的阳性人工选择的特征，以及HBB基因中的相关选择。我们的研究结果支持部分欧洲家鹅和中国家鹅的独立起源。此外，积极的人工选择和功能限制的放松在家鹅飞行性能退化中起重要作用。
Flyability is the most discrepant trait between modern-day geese and their wild ancestors, and the degeneration of flyability is a key marker of the successful domestication of wild geese. In light of the relatively short history of domestic geese, intense artificial selection is thought to play an important role in the degeneration of flyability. However, the underlying mechanism behind this phenomenon has seldom been investigated. In this study, we applied a molecular evolutionary approach to the evaluation of partial breeds of domestic geese in order to look for genes involved in the selection pressure toward degeneration of flyability. The haplotype networks, pairwise fixation index (FST) values, and analysis of molecular variance results all clearly illustrated a population variance between Landes geese and partial Chinese domestic geese. We also detected signatures of positive artificial selection in the COX2 and COX3 genes, and related selection in the HBB gene. Our results support the independent origins of partial European domestic geese and Chinese domestic geese. In addition, both positive artificial selection and the relaxation of functional constraints appeared to play important roles in the degeneration of flyability in domestic geese.
登录
查看更多内容
影响因子：
4.5
作者：
Storz JF;Sabatino SJ;Hoffmann FG;Gering EJ;Moriyama H;Ferrand N;Monteiro B;Nachman MW
通讯作者：
Nachman MW
DOI：
10.1073/pnas.0401720101
发表时间：
2004-07-20
影响因子：
11.1
作者：
Innan, H;Kim, Y
通讯作者：
Kim, Y
影响因子：
3.8
作者：
Li, J.;Yang, H.;Zhang, Y-P
通讯作者：
Zhang, Y-P
加拉帕戈斯菌神丧失飞行的演变的遗传标志。
DOI：
10.1126/science.aal3345
发表时间：
2017-06-02
期刊：
Science (New York, N.Y.)
影响因子：
--
作者：
Burga A;Wang W;Ben-David E;Wolf PC;Ramey AM;Verdugo C;Lyons K;Parker PG;Kruglyak L
通讯作者：
Kruglyak L
影响因子：
5.8
作者：
Larkin, M. A.;Blackshields, G.;Higgins, D. G.
通讯作者：
Higgins, D. G.