Beyond dueling: roles of the type VI secretion system in microbiome modulation, pathogenesis and stress resistance.
Beyond dueling: roles of the type VI secretion system in microbiome modulation, pathogenesis and stress resistance.
复制标题
超越决斗:VI 型分泌系统在微生物组调节、发病机制和应激抵抗中的作用
DOI:
10.1007/s44154-021-00008-z
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发表时间:
2021-11-03
期刊:
影响因子:
--
通讯作者:
Shen, Xihui
中科院分区:
文献类型:
--
作者:
Lin, Jinshui;Xu, Lei;Yang, Jianshe;Wang, Zhuo;Shen, Xihui
Bacteria inhabit diverse and dynamic environments, where nutrients may be limited and toxic chemicals can be prevalent. To adapt to these stressful conditions, bacteria have evolved specialized protein secretion systems, such as the type VI secretion system (T6SS) to facilitate their survival. As a molecular syringe, the T6SS expels various effectors into neighboring bacterial cells, eukaryotic cells, or the extracellular environment. These effectors improve the competitive fitness and environmental adaption of bacterial cells. Although primarily recognized as antibacterial weapons, recent studies have demonstrated that T6SSs have functions beyond interspecies competition. Here, we summarize recent research on the role of T6SSs in microbiome modulation, pathogenesis, and stress resistance.
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影响因子:
4.6
作者:
Chen WJ;Kuo TY;Hsieh FC;Chen PY;Wang CS;Shih YL;Lai YM;Liu JR;Yang YL;Shih MC
通讯作者:
Shih MC
影响因子:
4.5
作者:
Brunet YR;Bernard CS;Gavioli M;Lloubès R;Cascales E
通讯作者:
Cascales E
影响因子:
64.5
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通讯作者:
Mekalanos JJ
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3.4
作者:
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通讯作者:
Wu, Yong
DOI:
10.1016/j.ijbiomac.2019.04.026
发表时间:
2019-07-15
影响因子:
8.2
作者:
Dutta, Priyanka;Jijumon, A. S.;Maiti, Sankar
通讯作者:
Maiti, Sankar