Biological characteristics of a cerebellar mass regrowing after removal in a patient with lhermitte-duclos disease: emission tomography studies.
Biological characteristics of a cerebellar mass regrowing after removal in a patient with lhermitte-duclos disease: emission tomography studies.
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DOI：
10.1159/000362118
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发表时间：
2014-01
影响因子：
0.7
通讯作者：
Terasaki K
中科院分区：
文献类型：
--
作者：
Saito H;Ogasawara K;Beppu T;Matsuura H;Terasaki K
Lhermitte-Duclos disease is a rare disorder characterized by a slowly enlarging mass in the cerebellum. The exact nature of this lesion remains unclear, but it has been variously characterized as hypertrophy, hamartoma or benign neoplasm. Single-photon emission computed tomography (SPECT) with 123I-iomazenil and 99mTc-ethyl cysteinate dimer (ECD) display central benzodiazepine receptors that are widely distributed in the normal brain cortex, a combination of brain perfusion, enzymatic activity and blood-brain barrier function, respectively. This report describes the case of a 30-year-old man who developed Lhermitte-Duclos disease. The mass regrew after a subtotal removal 13 years earlier. The cerebellar lesion exhibited hyperperfusion and hypermetabolism on blood flow and a metabolic rate of oxygen imaging on 15O-gas positron emission tomography (PET), as well as a hyperactivity and a defect in the uptake on 99mTc-ECD and 123I-iomazenil SPECT imaging, respectively. The present Lhermitte-Duclos lesion might have the biological characteristics of both hypertrophy and neoplasm, from the perspective of results from 15O-gas PET, 99mTc-ECD and 123I-iomazenil SPECT.
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影响因子：
3.9
作者：
Nakagawa, Toshio;Maeda, Masayuki;Takeda, Kan
通讯作者：
Takeda, Kan
影响因子：
2.6
作者：
LAMMERTSMA, AA;WISE, RJS;JONES, T
通讯作者：
JONES, T
影响因子：
9.3
作者：
Chida, Kohei;Ogasawara, Kuniaki;Ogawa, Akira
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Ogawa, Akira
影响因子：
8.3
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Nakagawara, J;Sperling, B;Lassen, NA
通讯作者：
Lassen, NA
影响因子：
3.9
作者：
Goto, Yuko;Hashimoto, Naoya;Yoshimine, Toshiki
通讯作者：
Yoshimine, Toshiki