Clinical Findings of COVID-19 Patients Admitted to Intensive Care Units in Guangdong Province, China: A Multicenter, Retrospective, Observational Study.
Clinical Findings of COVID-19 Patients Admitted to Intensive Care Units in Guangdong Province, China: A Multicenter, Retrospective, Observational Study.
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DOI：
10.3389/fmed.2020.576457
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发表时间：
2020
影响因子：
3.9
通讯作者：
Li Y
中科院分区：
文献类型：
--
作者：
Xu Y;Xu Z;Liu X;Cai L;Zheng H;Huang Y;Zhou L;Huang L;Ling Y;Deng L;Li J;Chen S;Liu D;Lin Z;Zhou L;He W;Zhong N;Liu X;Li Y
背景：关于武汉市以外中国(新冠肺炎)2019年冠状病毒病危重患者的信息很少。我们的目的是描述广东省重症监护病房(ICU)收治的新冠肺炎患者的临床特征、治疗和转归。方法：在这项多中心、回顾性、观察性研究中，我们纳入了广东省7个ICU的连续新冠肺炎患者。收集了人口学数据、症状、实验室发现、合并症、治疗和结果。对插管和不插管患者的数据进行比较。结果：纳入研究医院ICU的新冠肺炎患者45例，平均年龄(56.7±15.4)岁，男性29例(64.4%)。发病时最常见的症状是发烧和咳嗽。大多数患者表现为淋巴细胞减少和乳酸脱氢酶升高。所有患者都开始了抗病毒药物的治疗。36例患者(80%)在ICU入院时出现急性呼吸窘迫综合征，15例(33.3%)感染性休克。气管插管20例(44.4%)，体外膜肺氧合10例(22.2%)。60d死亡率为4.4%(2/45)。结论：ICU收治的新冠肺炎患者以发热、淋巴细胞减少、急性呼吸衰竭和多器官功能障碍为特征。广东省ICU患者病死率较低，样本量较小。
Background: Information about critically ill patients with coronavirus disease 2019 (COVID-19) in China but outside of Wuhan is scarce. We aimed to describe the clinical features, treatment, and outcomes of patients with COVID-19 admitted to the intensive care unit (ICU) in Guangdong Province. Methods: In this multicenter, retrospective, observational study, we enrolled consecutive patients with COVID-19 who were admitted to seven ICUs in Guangdong Province. Demographic data, symptoms, laboratory findings, comorbidities, treatment, and outcomes were collected. Data were compared between patients with and without intubation. Results: A total of 45 COVID-19 patients required ICU admission in the study hospitals [mean age 56.7 ± 15.4 years, 29 males (64.4%)]. The most common symptoms at onset were fever and cough. Most patients presented with lymphopenia and elevated lactate dehydrogenase. Treatment with antiviral drugs was initiated in all patients. Thirty-six patients (80%) developed acute respiratory distress syndrome at ICU admission, and 15 (33.3%) septic shock. Twenty patients (44.4%) were intubated, and 10 (22.2%) received extracorporeal membrane oxygenation. The 60-day mortality was 4.4% (2 of 45). Conclusion: COVID-19 patients admitted to ICU were characterized by fever, lymphopenia, acute respiratory failure, and multiple organ dysfunction. The mortality of ICU patients in Guangdong Province was relatively low with a small sample size.
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DOI：
10.1186/cc11454
发表时间：
2013-02-04
期刊：
Critical care (London, England)
影响因子：
--
作者：
Kellum JA;Lameire N;KDIGO AKI Guideline Work Group
通讯作者：
KDIGO AKI Guideline Work Group
影响因子：
3.4
作者：
Wang, Jiajia;Xu, Hua;Yang, Xinjing;Zhao, Daguo;Liu, Shenglan;Sun, Xue;Huang, Jian-an;Guo, Qiang
通讯作者：
Guo, Qiang
预测病毒性肺炎患者死亡风险的临床特征：MuLBSTA 评分
影响因子：
5.2
作者：
Guo, Lingxi;Wei, Dong;Qu, Jieming
通讯作者：
Qu, Jieming
影响因子：
20.6
作者：
Tang, Xiaolu;Wu, Changcheng;Lu, Jian
通讯作者：
Lu, Jian
DOI：
10.2169/internalmedicine.0316-17
发表时间：
2018-07-01
期刊：
Internal medicine (Tokyo, Japan)
影响因子：
--
作者：
Ito T;Akamatsu K;Ukimura A;Fujisaka T;Ozeki M;Kanzaki Y;Ishizaka N
通讯作者：
Ishizaka N