Diagnosis, evaluation, and management of acute kidney injury: a KDIGO summary (Part 1).

Diagnosis, evaluation, and management of acute kidney injury: a KDIGO summary (Part 1).
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DOI:
10.1186/cc11454
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发表时间:
2013-02-04
期刊:
Critical care (London, England)
影响因子:
--
通讯作者:
KDIGO AKI Guideline Work Group
KDIGO AKI Guideline Work Group
中科院分区:
其他
文献类型:
--
作者:
Kellum JA;Lameire N;KDIGO AKI Guideline Work Group

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急性肾损伤(AKI)是一种常见而严重的问题,影响数百万人,并导致许多人死亡和残疾。2012年,肾脏疾病:改善全球结局完成了AKI的第一个国际多学科临床实践指南。该指南以证据审查和评价为基础,涵盖AKI的定义、风险评估、评价、预防和治疗。在这篇综述中,我们总结了该指南的关键方面,包括AKI的定义和分期,以及评估和非透析管理。造影剂诱发的AKI和肾脏替代治疗的管理将在单独的综述中讨论。治疗建议是基于对相关试验的系统评价。证据质量和建议强度的评估遵循建议分级评估、发展和评估方法。讨论了证据的局限性,并为每项建议提供了详细的理由。
Acute kidney injury (AKI) is a common and serious problem affecting millions and causing death and disability for many. In 2012, Kidney Disease: Improving Global Outcomes completed the first ever, international, multidisciplinary, clinical practice guideline for AKI. The guideline is based on evidence review and appraisal, and covers AKI definition, risk assessment, evaluation, prevention, and treatment. In this review we summarize key aspects of the guideline including definition and staging of AKI, as well as evaluation and nondialytic management. Contrast-induced AKI and management of renal replacement therapy will be addressed in a separate review. Treatment recommendations are based on systematic reviews of relevant trials. Appraisal of the quality of the evidence and the strength of recommendations followed the Grading of Recommendations Assessment, Development and Evaluation approach. Limitations of the evidence are discussed and a detailed rationale for each recommendation is provided.
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