Ciguatera fish poisoning in the Pacific Islands (1998 to 2008).
Ciguatera fish poisoning in the Pacific Islands (1998 to 2008).
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DOI：
10.1371/journal.pntd.0001416
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发表时间：
2011-12
影响因子：
3.8
通讯作者：
Lewis RJ
中科院分区：
文献类型：
--
作者：
Skinner MP;Brewer TD;Johnstone R;Fleming LE;Lewis RJ
雪卡毒是一种鱼类中毒，在整个热带地区都有发生，特别是在脆弱的岛屿社区，如发展中太平洋岛屿国家和地区。食用受雪卡毒素污染的鱼类后，人们报告了一系列急性神经系统，胃肠道和心脏症状，有些人经历了持续数周至数月的慢性神经系统症状。不幸的是，人们对疾病的真实程度及其对人类社区和生态系统健康的影响仍然知之甚少。通过电子邮件向太平洋岛屿国家卫生和渔业当局发送了一份调查问卷，以量化雪卡毒素的程度。采用t检验、发生率比、等级相关和回归分析等方法对数据进行分析。17个太平洋岛屿国家报告了39，677例病例，1998-2008年整个区域的平均年发病率为每100，000人194例，而1973-1983年报告的年发病率为每100，000人104例。根据在这两个时期报告的太平洋岛屿信息和通信技术，在这两个时期之间，雪卡毒素的年发病率增加了60%。考虑到报告不足的情况，在过去35年中，估计有50万太平洋岛民可能受到雪卡毒素的影响。这一发病率水平超过了当地和全球先前对雪卡毒素的估计，并将雪卡毒素的地位提高到具有重大公共卫生意义的急性和慢性疾病。为了解决这一重大的公共卫生问题，预计这一问题将随着环境变化而增加，需要资金充足的多学科研究小组将研究进展转化为实际的管理解决方案。雪卡毒鱼类中毒发生在整个热带地区。在食用受污染的珊瑚礁鱼类后，人们报告了一系列急性神经系统，胃肠道和心脏症状，其中一些人经历了持续数周至数月的慢性神经系统症状。雪卡毒主要是由甘比盘属底栖微藻的毒素引起的，这些毒素通过海洋食物链在珊瑚鱼体内生物积累。不幸的是，疾病的真实程度及其对人类社区和生态系统的影响仍然没有得到很好的了解。利用从太平洋岛屿国家和地区卫生和渔业当局收集的数据，我们发现从1988-2008年到1973-1983年，雪卡毒素的年发病率增加了60%，估计超过50万太平洋岛民一生中可能遭受雪卡毒素的影响。随着珊瑚礁的持续退化和全球变暖，预计雪卡毒的发生率将继续上升，发展中的太平洋岛屿和岛屿国家可能受到最大的影响，东南亚的群岛也可能受到影响。尽管存在这一威胁，但用于可能导致在地方、区域或全球更好地管理这一问题的研究的资金却很少。
Ciguatera is a type of fish poisoning that occurs throughout the tropics, particularly in vulnerable island communities such as the developing Pacific Island Countries and Territories (PICTs). After consuming ciguatoxin-contaminated fish, people report a range of acute neurologic, gastrointestinal, and cardiac symptoms, with some experiencing chronic neurologic symptoms lasting weeks to months. Unfortunately, the true extent of illness and its impact on human communities and ecosystem health are still poorly understood. A questionnaire was emailed to the Health and Fisheries Authorities of the PICTs to quantify the extent of ciguatera. The data were analyzed using t-test, incidence rate ratios, ranked correlation, and regression analysis. There were 39,677 reported cases from 17 PICTs, with a mean annual incidence of 194 cases per 100,000 people across the region from 1998–2008 compared to the reported annual incidence of 104/100,000 from 1973–1983. There has been a 60% increase in the annual incidence of ciguatera between the two time periods based on PICTs that reported for both time periods. Taking into account under-reporting, in the last 35 years an estimated 500,000 Pacific islanders might have suffered from ciguatera. This level of incidence exceeds prior ciguatera estimates locally and globally, and raises the status of ciguatera to an acute and chronic illness with major public health significance. To address this significant public health problem, which is expected to increase in parallel with environmental change, well-funded multidisciplinary research teams are needed to translate research advances into practical management solutions. Ciguatera fish poisoning occurs throughout the tropics. After consuming contaminated coral reef fish, people report a range of acute neurologic, gastrointestinal, and cardiac symptoms, with some experiencing chronic neurologic symptoms lasting weeks to months. Ciguatera is largely caused by toxins from benthic microalgae of the genera Gambierdiscus that are bioaccumulated in reef fish through the marine food chain. Unfortunately, the true extent of illness and its impact on human communities and ecosystems are still not well understood. Using data gathered from Health and Fisheries Authorities of the Pacific Island Countries and Territories we identified a 60% increase in the annual incidence of ciguatera from 1988–2008 to 1973–1983 and estimate over 500,000 Pacific islanders might have suffered from ciguatera in their lifetime. The incidence of ciguatera is expected to continue to rise in conjunction with continued reef degradation and global warming, with greatest impact likely to be experienced in the developing PICTs and potentially the archipelagoes of southeast Asia. Despite this threat, little funding is available for research that might lead to better management of the problem either locally, regionally or globally.
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DOI：
10.1046/j.1526-0992.1999.09903.x
发表时间：
1999-03-01
期刊：
ECOSYSTEM HEALTH
影响因子：
--
作者：
Hales, S;Weinstein, P;Woodward, A
通讯作者：
Woodward, A
影响因子：
2.8
作者：
Llewellyn, Lyndon E.
通讯作者：
Llewellyn, Lyndon E.
影响因子：
6.6
作者：
Rongo, Teina;van Woesik, Robert
通讯作者：
van Woesik, Robert
影响因子：
2.8
作者：
Tester, Patricia A.;Feldman, Rebecca L.;Litaker, R. Wayne
通讯作者：
Litaker, R. Wayne
影响因子：
2.8
作者：
Chinain, Mireille;Darius, H. Taiana;Pauillac, Serge
通讯作者：
Pauillac, Serge