Neural basis of goal-driven changes in knowledge activation.

Neural basis of goal-driven changes in knowledge activation.
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DOI:
10.1111/ejn.14196
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发表时间:
2018-12
期刊:
The European journal of neuroscience
影响因子:
--
通讯作者:
Cabeza R
Cabeza R
中科院分区:
其他
文献类型:
--
作者:
Wang WC;Brashier NM;Wing EA;Marsh EJ;Cabeza R

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根据一个人的目标,存储的知识的不同方面被访问。几十年的行为学研究证明了知识的灵活运用,但很少有神经影像学研究涉及这些问题。我们使用表征相似性分析,以调查是否大脑活动和语句的语义结构之间的关系不同的两个任务假设不同的程度,知识的访问:判断真理(语义任务)和判断古老(情节任务)。在真理的判断,但不是旧/新的识别判断,一个左偏网络先前与语义记忆表现出相关性与语义结构。在神经层面上,当人们专注于不同的目标时,会以不同的方式激活知识表征。目前的研究结果表明,多变量方法在表征知识存储和检索方面的潜力,以及它塑造我们的理解和长期记忆的方式。
Depending on a person’s goals, different aspects of stored knowledge are accessed. Decades of behavioral work document the flexible use of knowledge, but little neuroimaging work speaks to these questions. We used representational similarity analysis to investigate whether the relationship between brain activity and semantic structure of statements varied in two tasks hypothesized to differ in the degree to which knowledge is accessed: judging truth (semantic task) and judging oldness (episodic task). During truth judgments, but not old/new recognition judgments, a left-lateralized network previously associated with semantic memory exhibited cor-relations with semantic structure. At a neural level, people activate knowledge representations in different ways when focused on different goals. The present results demonstrate the potential of multivariate approaches in characterizing knowledge storage and retrieval, as well as the ways that it shapes our understanding and long-term memory.
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