Anatomical atlas-guided diffuse optical tomography of brain activation.

Anatomical atlas-guided diffuse optical tomography of brain activation.
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DOI:
10.1016/j.neuroimage.2009.07.033
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发表时间:
2010-01-01
期刊:
影响因子:
5.7
通讯作者:
Wells, Williams, III
Wells, Williams, III
中科院分区:
医学1区
文献类型:
--
作者:
Custo, Anna;Boas, David A.;Tsuzuki, Daisuke;Dan, Ippeita;Mesquita, Rickson;Fischl, Bruce;Grimson, W. Eric L.;Wells, Williams, III

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我们描述了一种神经成像方案,利用人类头部的解剖图谱来指导人类大脑激活的漫射光学断层扫描。该方案通过对三名健康受试者的正中神经刺激的血流动力学反应成像来证明,并将使用头部图谱获得的图像与使用受试者特定头部解剖获得的图像进行比较。结果表明,使用头部图谱解剖可以重建大脑激活的位置到预期的大脑回,与受试者特定头部解剖获得的结果一致。这种新方法的好处在于消除了对特定受试者头部解剖的需要,从而消除了对特定受试者MRI的需要,从而提高了对大脑激活的漫射光学断层扫描图像的解剖解释。
We describe a neuro imaging protocol that utilizes an anatomical atlas of the human head to guide Diffuse optical tomography of human brain activation. The protocol is demonstrated by imaging the hemodynamic response to median nerve stimulation in three healthy subjects, and comparing the images obtained using a head atlas with the images obtained using the subject-specific head anatomy. The results indicate that using the head atlas anatomy it is possible to reconstruct the location of the brain activation to the expected gyrus of the brain, in agreement with the results obtained with the subject-specific head anatomy. The benefits of this novel method derive from eliminating the need for subject-specific head anatomy and thus obviating the need for a subject-specific MRI to improve the anatomical interpretation of Diffuse optical tomography images of brain activation.
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发表时间: 1999-02-01
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