Race and Sex Differences in Vital Signs Associated with COVID-19 and Flu Diagnoses in Mississippi.

Race and Sex Differences in Vital Signs Associated with COVID-19 and Flu Diagnoses in Mississippi.
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DOI:
10.1007/s40615-021-01213-2
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发表时间:
2023-03
影响因子:
3.9
通讯作者:
Garrett MR
Garrett MR
中科院分区:
医学4区
文献类型:
--
作者:
Martin BE;Garrett MR

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早期发现病毒感染,如COVID-19和流感,有可能通过早期干预策略降低发病率、死亡率和疾病传播的风险。例如,检测生命体征的变化有可能更快地诊断呼吸道病毒疾病。本研究的目的是利用密西西比大学医学中心的广泛临床数据库(EPIC),调查COVID-19和流感诊断患者的体温、脉率、血压(BP)和呼吸率之间的关联。数据来自1,363 COVID-19(2020年3月3日至2021年2月27日)和507流感(2017年10月1日至2018年9月30日)报告人口统计学维度的确诊患者(年龄、第一人种和性别)和诊室访视维度获得(BMI、舒张压、脉率、呼吸率、收缩压和体温),包括诊断日和首次独特诊断前后60天的额外就诊访视。COVID-19或流感患者的肥胖比例不成比例,93%的COVID-19和79%的流感患者BMI ≥ 30。最引人注目的是,50-64岁的黑人妇女不成比例地承担着疾病负担。在诊断时,所有患者的体温均显著升高,但脉搏率仅在流感诊断时显著升高,血压无显著差异。我们的研究结果表明,在流行病和大流行事件期间,需要更完整的人口统计学和办公室访问维度数据,并支持进一步研究,以了解生命体征和预测呼吸系统疾病之间的关联。在线版本包含补充材料,可通过10.1007/s40615-021-01213-2获得。
Early detection of viral infections, such as COVID-19 and flu, have potential to reduce risk of morbidity, mortality, and disease transmission through earlier intervention strategies. For example, detecting changes in vital signs have the potential to more rapidly diagnose respiratory virus diseases. The objective of this study was to utilize the University of Mississippi Medical Center’s extensive clinical database (EPIC) to investigate associations between temperature, pulse rate, blood pressure (BP), and respiration rate in COVID-19 and flu diagnosed patients. Data from 1,363 COVID-19 (March 3, 2020, to February 27, 2021) and 507 flu (October 1, 2017, to September 30, 2018) diagnosed patients with reported demographic dimensions (age, first race, and sex) and office visit dimensions (BMI, diastolic BP, pulse rate, respiration rate, systolic BP, and temperature) was obtained, including day of diagnosis and additional encounter visits 60 days before and after first unique diagnosis. Patients with COVID-19 or flu were disproportionately obese, with 93% of COVID-19 and 79% of flu patients with BMI ≥ 30. Most striking, Black women 50–64 years of age disproportionately carried the burden of disease. At the time of diagnosis, temperature was significantly increased for all patients, yet pulse rate was only significantly increased for flu diagnosis, and BP was not significantly different in either. Our findings show the need for more complete demographic and office visit dimension data from patients during epidemic and pandemic events and support further studies needed to understand association between vital signs and predicting respiratory disease. The online version contains supplementary material available at 10.1007/s40615-021-01213-2.
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