CATH: an expanded resource to predict protein function through structure and sequence.
CATH: an expanded resource to predict protein function through structure and sequence.
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DOI：
10.1093/nar/gkw1098
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发表时间：
2017-01-04
影响因子：
14.9
通讯作者：
Sillitoe I
中科院分区：
文献类型：
--
作者：
Dawson NL;Lewis TE;Das S;Lees JG;Lee D;Ashford P;Orengo CA;Sillitoe I
CATH-GENE3D蛋白结构分类数据库的最新版本最近发布（版本4.1，http://www.cathdb.info）。该资源包括超过30万个域结构，超过5300万个蛋白质结构域分类为2737个同源超家族，使上一个版本中预测的蛋白质结构域的数量增加了一倍。每日更新的CATH-B包含我们最新的域分配数据，为超过100万个其他蛋白质域提供了推定的分类。本文介绍了自2015年出版以来的过去两年中Cath-Gene3D资源的发展，包括：我们的结构和序列覆盖范围显着提高；在CATH中的功能家庭扩展；构建支持向量机（SVM）自动为超家族分配域；改进的搜索设施可以根据多个序列比对返回查询序列的比对；网页和下载网站的重新设计。
The latest version of the CATH-Gene3D protein structure classification database has recently been released (version 4.1, http://www.cathdb.info). The resource comprises over 300 000 domain structures and over 53 million protein domains classified into 2737 homologous superfamilies, doubling the number of predicted protein domains in the previous version. The daily-updated CATH-B, which contains our very latest domain assignment data, provides putative classifications for over 100 000 additional protein domains. This article describes developments to the CATH-Gene3D resource over the last two years since the publication in 2015, including: significant increases to our structural and sequence coverage; expansion of the functional families in CATH; building a support vector machine (SVM) to automatically assign domains to superfamilies; improved search facilities to return alignments of query sequences against multiple sequence alignments; the redesign of the web pages and download site.
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影响因子：
14.9
作者：
Finn RD;Clements J;Arndt W;Miller BL;Wheeler TJ;Schreiber F;Bateman A;Eddy SR
通讯作者：
Eddy SR
DOI：
10.1093/bioinformatics/bts565
发表时间：
2012-12-01
期刊：
Bioinformatics (Oxford, England)
影响因子：
--
作者：
Fu L;Niu B;Zhu Z;Wu S;Li W
通讯作者：
Li W
影响因子：
12.3
作者：
Jiang Y;Oron TR;Clark WT;Bankapur AR;D'Andrea D;Lepore R;Funk CS;Kahanda I;Verspoor KM;Ben-Hur A;Koo da CE;Penfold-Brown D;Shasha D;Youngs N;Bonneau R;Lin A;Sahraeian SM;Martelli PL;Profiti G;Casadio R;Cao R;Zhong Z;Cheng J;Altenhoff A;Skunca N;Dessimoz C;Dogan T;Hakala K;Kaewphan S;Mehryary F;Salakoski T;Ginter F;Fang H;Smithers B;Oates M;Gough J;Törönen P;Koskinen P;Holm L;Chen CT;Hsu WL;Bryson K;Cozzetto D;Minneci F;Jones DT;Chapman S;Bkc D;Khan IK;Kihara D;Ofer D;Rappoport N;Stern A;Cibrian-Uhalte E;Denny P;Foulger RE;Hieta R;Legge D;Lovering RC;Magrane M;Melidoni AN;Mutowo-Meullenet P;Pichler K;Shypitsyna A;Li B;Zakeri P;ElShal S;Tranchevent LC;Das S;Dawson NL;Lee D;Lees JG;Sillitoe I;Bhat P;Nepusz T;Romero AE;Sasidharan R;Yang H;Paccanaro A;Gillis J;Sedeño-Cortés AE;Pavlidis P;Feng S;Cejuela JM;Goldberg T;Hamp T;Richter L;Salamov A;Gabaldon T;Marcet-Houben M;Supek F;Gong Q;Ning W;Zhou Y;Tian W;Falda M;Fontana P;Lavezzo E;Toppo S;Ferrari C;Giollo M;Piovesan D;Tosatto SC;Del Pozo A;Fernández JM;Maietta P;Valencia A;Tress ML;Benso A;Di Carlo S;Politano G;Savino A;Rehman HU;Re M;Mesiti M;Valentini G;Bargsten JW;van Dijk AD;Gemovic B;Glisic S;Perovic V;Veljkovic V;Veljkovic N;Almeida-E-Silva DC;Vencio RZ;Sharan M;Vogel J;Kansakar L;Zhang S;Vucetic S;Wang Z;Sternberg MJ;Wass MN;Huntley RP;Martin MJ;O'Donovan C;Robinson PN;Moreau Y;Tramontano A;Babbitt PC;Brenner SE;Linial M;Orengo CA;Rost B;Greene CS;Mooney SD;Friedberg I;Radivojac P
通讯作者：
Radivojac P
影响因子：
10.7
作者：
Katoh K;Standley DM
通讯作者：
Standley DM
影响因子：
14.9
作者：
UniProt Consortium
通讯作者：
UniProt Consortium