The SirT3 divining rod points to oxidative stress.
The SirT3 divining rod points to oxidative stress.
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DOI:
10.1016/j.molcel.2011.05.008
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发表时间:
2011-06-10
期刊:
影响因子:
16
通讯作者:
Guarente L
中科院分区:
文献类型:
--
作者:
Bell EL;Guarente L
Sirtuins are NAD-dependent deacetylases that counter aging and diseases of aging. Sirtuin research has focused on SirT1, which deacetylates transcription factors and cofactors in the nucleus. More recent findings highlight SirT3 as a mitochondrial sirtuin that regulates metabolism and oxidative stress. This review focuses on new data linking SirT3 to management of reactive oxygen species from mitochondria, which may have profound implications for aging and late-onset diseases
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影响因子:
16
作者:
Hallows WC;Yu W;Smith BC;Devries MK;Ellinger JJ;Someya S;Shortreed MR;Prolla T;Markley JL;Smith LM;Zhao S;Guan KL;Denu JM
通讯作者:
Denu JM
影响因子:
10.5
作者:
Cohen, Dena E.;Supinski, Andrea M.;Guarente, Leonard P.
通讯作者:
Guarente, Leonard P.
影响因子:
14.9
作者:
Garcia, Christine Kim;Wright, Woodring E;Shay, Jerry W
通讯作者:
Shay, Jerry W
影响因子:
29
作者:
Banks AS;Kon N;Knight C;Matsumoto M;Gutiérrez-Juárez R;Rossetti L;Gu W;Accili D
通讯作者:
Accili D
DOI:
10.1146/annurev.pathol.4.110807.092250
发表时间:
2010
期刊:
Annual review of pathology
影响因子:
--
作者:
Haigis MC;Sinclair DA
通讯作者:
Sinclair DA