Fusobacterium nucleatum and colorectal cancer: A review.

Fusobacterium nucleatum and colorectal cancer: A review.
复制标题

具核梭杆菌与结直肠癌:综述

DOI:
10.4251/wjgo.v10.i3.71
复制
发表时间:
2018-03-15
影响因子:
3
通讯作者:
Liu HL
Liu HL
中科院分区:
医学4区
文献类型:
--
作者:
Shang FM;Liu HL

文献摘要

参考文献

被引文献

相似文献

具核梭杆菌(F. nucleatum)是口腔中的一种革兰氏阴性专性厌氧菌,在多种口腔疾病中发挥作用,包括牙周炎和牙龈炎。最近,一些研究报道,与邻近正常组织相比,人类结直肠腺瘤和癌中具核梭杆菌的水平显着升高。一些研究人员还证明,具核梭菌与结直肠癌明显相关,并促进结直肠肿瘤的发展。在这篇综述中,我们总结了最近关于具核梭菌及其在结直肠癌中的作用的报道,重点介绍了结直肠癌中具核梭杆菌的检测方法、发病机制、免疫状态以及针对具核梭杆菌的结直肠癌预防策略。
Fusobacterium nucleatum (F. nucleatum) is a Gram-negative obligate anaerobe bacterium in the oral cavity and plays a role in several oral diseases, including periodontitis and gingivitis. Recently, several studies have reported that the level of F. nucleatum is significantly elevated in human colorectal adenomas and carcinomas compared to that in adjacent normal tissue. Several researchers have also demonstrated that F. nucleatum is obviously associated with colorectal cancer and promotes the development of colorectal neoplasms. In this review, we have summarized the recent reports on F. nucleatum and its role in colorectal cancer and have highlighted the methods of detecting F. nucleatum in colorectal cancer, the underlying mechanisms of pathogenesis, immunity status, and colorectal cancer prevention strategies that target F. nucleatum.
功能表达克隆将COX-2鉴定为抗原特异性癌症免疫的抑制剂。
DOI: 10.1038/cddis.2014.531
发表时间: 2014-12-11
影响因子: 9
作者:
Göbel C;Breitenbuecher F;Kalkavan H;Hähnel PS;Kasper S;Hoffarth S;Merches K;Schild H;Lang KS;Schuler M
通讯作者: Schuler M
DOI: 10.1053/j.gastro.2016.07.030
发表时间: 2016-11
期刊: Gastroenterology
影响因子: 29.4
作者:
Cao Y;Nishihara R;Qian ZR;Song M;Mima K;Inamura K;Nowak JA;Drew DA;Lochhead P;Nosho K;Morikawa T;Zhang X;Wu K;Wang M;Garrett WS;Giovannucci EL;Fuchs CS;Chan AT;Ogino S
通讯作者: Ogino S
DOI: 10.18632/oncotarget.4209
发表时间: 2015-09-08
期刊: Oncotarget
影响因子: --
作者:
Binder Gallimidi A;Fischman S;Revach B;Bulvik R;Maliutina A;Rubinstein AM;Nussbaum G;Elkin M
通讯作者: Elkin M
DOI: 10.1086/341899
发表时间: 2002-08-15
影响因子: 11.8
作者:
Finegold, SM;Flynn, MJ;Wynne, B
通讯作者: Wynne, B
DOI: 10.1101/gr.126516.111
发表时间: 2012-02-01
期刊: GENOME RESEARCH
影响因子: 7
作者:
Castellarin, Mauro;Warren, Rene L.;Holt, Robert A.
通讯作者: Holt, Robert A.