Feasibility evaluation of a new irradiation technique: three-dimensional unicursal irradiation with the Vero4DRT (MHI-TM2000).
Feasibility evaluation of a new irradiation technique: three-dimensional unicursal irradiation with the Vero4DRT (MHI-TM2000).
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DOI：
10.1093/jrr/rrs076
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发表时间：
2013-03-01
影响因子：
2
通讯作者：
Hiraoka M
中科院分区：
文献类型：
--
作者：
Mizowaki T;Takayama K;Nagano K;Miyabe Y;Matsuo Y;Kaneko S;Kokubo M;Hiraoka M
Vero 4DRT（MHI-TM 2000）是一种新设计的独特的图像引导放射治疗系统，由O形环机架组成。该系统可以实现一种新的照射技术，其中机架头和O形环在照射期间分别围绕O形环的内圆周和O形环的垂直轴连续地且同时地旋转。该技术产生三维（3D）旋转动态适形弧照射，我们称之为“3D单行照射”。本研究的目的是提出的概念，并估计新的辐照技术的可行性和潜在的优势。碰撞地图开发的技术和3D单循环计划实验创建参考碰撞地图胰腺癌的情况下。此后，进行了3D单行、二维旋转动态适形弧照射（2D-DCART）和调强放射治疗（IMRT）计划之间的剂量学比较。在靶区和危及器官方面，3D单循环计划的剂量体积数据与2D-DCART和IMRT计划的剂量体积数据相当或有所改善。3D单行计划的预期监测单元（MU）数量仅比2D-DCART计划和IMRT计划的MU分别高7%和低22.1%。预计3D单行照射技术在治疗时间和剂量分布方面具有潜在优势，应在各种条件下进行验证，Vero 4DRT的未来版本完全实现了该功能。
The Vero4DRT (MHI-TM2000) is a newly designed unique image-guided radiotherapy system consisting of an O-ring gantry. This system can realize a new irradiation technique in which both the gantry head and O-ring continuously and simultaneously rotate around the inner circumference of the O-ring and the vertical axis of the O-ring, respectively, during irradiation. This technique creates three-dimensional (3D) rotational dynamic conformal arc irradiation, which we term ‘3D unicursal irradiation’. The aim of this study was to present the concept and to estimate feasibility and potential advantages of the new irradiation technique. Collision maps were developed for the technique and a 3D unicursal plan was experimentally created in reference to the collision map for a pancreatic cancer case. Thereafter, dosimetric comparisons among the 3D unicursal, a two-dimensionally rotational dynamic conformal arc irradiation (2D–DCART), and an intensity-modulated radiation therapy (IMRT) plan were conducted. Dose volume data of the 3D unicursal plan were comparable or improved compared to those of the 2D–DCART and IMRT plans with respect to both the target and the organs at risk. The expected monitor unit (MU) number for the 3D unicursal plan was only 7% higher and 22.1% lower than the MUs for the 2D–DCART plan and IMRT plan, respectively. It is expected that the 3D unicursal irradiation technique has potential advantages in both treatment time and dose distribution, which should be validated under various conditions with a future version of the Vero4DRT fully implemented the function.
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影响因子：
5.7
作者：
Depuydt, Tom;Verellen, Dirk;De Ridder, Mark
通讯作者：
De Ridder, Mark
影响因子：
5.7
作者：
Aoki, T;Nagata, Y;Hiraoka, M
通讯作者：
Hiraoka, M
影响因子：
5.7
作者：
Takayama, Kenji;Mizowaki, Takashi;Hiraoka, Masahiro
通讯作者：
Hiraoka, Masahiro
DOI：
10.1016/j.ijrobp.2006.04.044
发表时间：
2006-09-01
影响因子：
7
作者：
Kamino, Yuichiro;Takayama, Kenji;Hiraoka, Masahiro
通讯作者：
Hiraoka, Masahiro
影响因子：
4.8
作者：
COLOMBO, F;BENEDETTI, A;ZANARDO, A
通讯作者：
ZANARDO, A