Photodissociation mass spectrometry: new tools for characterization of biological molecules.
Photodissociation mass spectrometry: new tools for characterization of biological molecules.
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DOI:
10.1039/c3cs60444f
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发表时间:
2014-04-21
影响因子:
46.2
通讯作者:
Brodbelt JS
中科院分区:
文献类型:
--
作者:
Brodbelt JS
Photodissociation mass spectrometry combines the ability to activate and fragment ions using photons with the sensitive detection of the resulting product ions by mass spectrometry. The resulting combination affords a versatile tool for characterization of biological molecules. The scope and breadth of photodissociation mass spectrometry have increased substantially over the past decade as new research groups have entered the field and developed a number of innovative applications that illustrate the ability of photodissociation to produce rich fragmentation patterns, to cleave bonds selectively, and to target specific molecules based on incorporation of chromophores. This review focuses on many of the key developments in photodissociation mass spectrometry over the past decade with a particular emphasis on its applications to biological molecules.
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