Changes in Cerebral Cortical Thickness Related to Weight Loss Following Bariatric Surgery.
Changes in Cerebral Cortical Thickness Related to Weight Loss Following Bariatric Surgery.
复制标题
减肥手术后与体重减轻有关的脑皮质厚度的变化。
DOI：
10.1007/s11695-018-3317-6
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发表时间：
2018-08
期刊：
影响因子：
2.9
通讯作者：
Morton JM
中科院分区：
文献类型：
--
作者：
Bohon C;Garcia LC;Morton JM
大脑皮质厚度与记忆力和智力测试分数相关，可作为皮质灰质变化的衡量标准。先前的研究表明肥胖患者的皮质厚度减少。本研究旨在调查减肥手术后皮质厚度的变化。对五名患者的术前和术后六个月的磁共振成像 (MRI) 数据进行了分析，以评估皮质厚度的整体测量变化。没有患者失访。手术后大脑变化的初步趋势表明，体重过度减轻的患者大脑皮质厚度增加。这项研究的结果表明，对于体重减轻最大的人来说，皮质厚度的增加可能是减肥手术的额外好处，并表明需要使用更大的样本以及与神经认知测量（例如记忆回忆）的相关性进行进一步研究。
Cerebral cortical thickness is associated with memory recall and intelligence test scores and serves as a measure for changes in cortical grey matter. Previous studies suggest reduced cortical thickness in patients with obesity. This study aimed to investigate changes in cortical thickness following bariatric surgery. Magnetic resonance imaging (MRI) data of five patients were analyzed preoperatively and six months postoperatively to assess changes in global measures of cortical thickness. No patients were lost to follow-up. Preliminary trends of brain change following surgery suggest increases in cerebral cortical thickness in patients with greater excess weight loss. The results of this study suggest increases in cortical thickness may be an additional benefit of bariatric surgery for those with greatest weight loss and indicate the need for further investigation using larger samples and correlation with neurocognitive measures, such as memory recall.
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影响因子：
5.7
作者：
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通讯作者：
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影响因子：
5.7
作者：
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通讯作者：
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DOI：
10.1016/j.nicl.2014.09.013
发表时间：
2014
期刊：
NeuroImage. Clinical
影响因子：
--
作者：
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通讯作者：
Preissl H