ROLE OF RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B LIGAND (RANKL) AND OSTEOPROTEGERIN (OPG) IN PERIODONTAL BONE DESTRUCTION: A REVIEW

ROLE OF RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B LIGAND (RANKL) AND OSTEOPROTEGERIN (OPG) IN PERIODONTAL BONE DESTRUCTION: A REVIEW
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核因子 KAPPA B 配体受体激活剂 (RANKL) 和骨保护素 (OPG) 在牙周骨破坏中的作用:综述

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发表时间:
2014
期刊:
影响因子:
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通讯作者:
Archana Moon
Archana Moon
中科院分区:
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作者:
N. Moon;M. Khan;Archana Moon

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牙周病也称为牙周炎,是一种牙齿支持结构遭到破坏的慢性炎症性疾病。细菌感染是主要病因。细菌制剂刺激一系列局部炎症反应,包括免疫系统的激活,进而导致促炎细胞因子的激活和释放,以及吞噬细胞和淋巴细胞的激活。发生的组织破坏被认为是宿主对各种细菌剂反应的结果。在本综述中,我们总结了细胞因子核因子 Kappa B 配体受体激活剂 (RANKL) 和骨保护素 (OPG) 在牙周炎期间牙周骨破坏中的作用。
Periodontal Disease also called as Periodontitis is a chronic inflammatory disease in which there is destruction of tooth supporting structures. Bacterial infection is the main etiologic factor. The Bacterial agents stimulate a cascade of local inflammatory reactions including activation of immune system which in turn leads to activation and release of pro-inflammatory cytokines apart from activation of phagocytes and lymphocytes. The tissue destruction which occurs is believed to a consequence of host response to various bacterial agents. In the present review we summarize the role of cytokine Receptor Activator of Nuclear Factor Kappa B Ligand (RANKL) and Osteoprotegerin (OPG) in periodontal bone destruction during periodontitis.
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发表时间: 1994-06-01
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