Influence of stress on the development of psoriasis

Influence of stress on the development of psoriasis
复制标题

压力对牛皮癣发展的影响

DOI:
10.1111/ced.14105
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发表时间:
2020-04
影响因子:
4.1
通讯作者:
Jie Zheng
Jie Zheng
中科院分区:
医学4区
文献类型:
--
作者:
Hui Yang;Jie Zheng

文献摘要

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银屑病是一种常见的慢性炎症性皮肤病,由遗传和环境因素(包括压力)形成。许多研究和病例报告表明,压力是银屑病发展和恶化的主要因素。近几十年来,已经取得了很大的进展,扩大了我们的知识的病理生理过程联系压力银屑病。其主要途径涉及下丘脑-垂体-肾上腺轴、交感-肾上腺-髓质轴、外周神经系统和免疫系统。本文就应激与银屑病的关系及其机制作一综述。
Psoriasis is a common chronic inflammatory skin disease, which is shaped by genetics and environmental factors, including stress. Numerous studies and case reports have suggested that stress is a major contributor to the development and exacerbation of psoriasis. In recent decades, much progress has been made expanding our knowledge on the pathophysiological processes linking stress to psoriasis. The main pathways involve the hypothalamic–pituitary–adrenal axis, sympathetic–adrenal–medullary axis, peripheral nervous system and immune system. The aim of this review is to summarize current knowledge on the relationship between stress and psoriasis and the underlying mechanisms.
DOI: 10.1016/j.cyto.2011.06.002
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期刊: CYTOKINE
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