TLC-Based Fingerprinting Analysis of the Geographical Variation of Melastoma malabathricum in Inland and Archipelago Regions: A Rapid and Easy-to-Use Tool for Field Metabolomics Studies.
TLC-Based Fingerprinting Analysis of the Geographical Variation of Melastoma malabathricum in Inland and Archipelago Regions: A Rapid and Easy-to-Use Tool for Field Metabolomics Studies.
复制标题
DOI：
10.1021/acs.jnatprod.1c00622
复制
发表时间：
2022-01-28
影响因子：
5.1
通讯作者：
Hamann MT
中科院分区：
文献类型：
--
作者：
Mayasari D;Murti YB;Pratiwi SUT;Sudarsono S;Hanna G;Hamann MT
Malabathricum是一种印度-太平洋草药，传统上用于治疗许多疾病，如伤口，痢疾，腹泻，牙痛和糖尿病。本研究的目的是评估M代谢谱的变异性。malabathricum在其地理分布。采用薄层色谱法（TLC），从印尼的陆地和群岛地区采集的标本进行了分析，结合化学计量学工具：主成分分析（PCA）和层次聚类分析（HCA）的代谢指纹分析密度。PC 1和PC 2分别占41.90%和20.36%。我们的研究结果表明，在实地收集工作中考虑地理分布的重要性，因为它们表明了M.薄层色谱分析表明，该化合物具有良好的生物活性。
Melastoma malabathricum is an Indo-Pacific herb that has been used traditionally to treat numerous ailments such as wounds, dysentery, diarrhea, toothache, and diabetes. The objective of this study was to evaluate the variability of the metabolic profiles of M. malabathricum across its geographic distribution. By employing thin layer chromatography (TLC), specimens collected from six terrestrial and archipelago regions of Indonesia were analyzed by densitometry for metabolomic fingerprinting analysis combined with chemometric tools: principal component analysis (PCA) and hierarchical cluster analysis (HCA). Two PCAs were identified as PC1 and PC2 with 41.90% and 20.36%, respectively. Our results indicate the importance of considering geographic distribution during field-collection efforts since they demonstrate regional metabolic variation in secondary metabolites of M. malabathricum, as illustrated by TLC and their biological activities.
登录
查看更多内容
影响因子：
4.1
作者：
Tian, Run-tao;Xie, Pei-shan;Liu, He-ping
通讯作者：
Liu, He-ping
DOI：
10.3844/ajidsp.2013.46.58
发表时间：
2013-01-01
期刊：
AMERICAN JOURNAL OF INFECTIOUS DISEASES
影响因子：
--
作者：
Alwash, Mourouge;Ibrahim, Nazlina;Ahmad, Wan
通讯作者：
Ahmad, Wan
影响因子：
8.8
作者：
Petropoulos, Spyridon A.;Levizou, Efi;Ferreira, Isabel C. F. R.
通讯作者：
Ferreira, Isabel C. F. R.
DOI：
10.1155/2012/258434
发表时间：
2012
期刊：
Evidence-based complementary and alternative medicine : eCAM
影响因子：
--
作者：
Joffry SM;Yob NJ;Rofiee MS;Affandi MM;Suhaili Z;Othman F;Akim AM;Desa MN;Zakaria ZA
通讯作者：
Zakaria ZA
影响因子：
2.2
作者：
Ozay, Yusuf;Guzel, Sevda;Darcan, Sinan
通讯作者：
Darcan, Sinan