Assessment of novel binocular colour, motion and contrast tests in glaucoma
Assessment of novel binocular colour, motion and contrast tests in glaucoma
复制标题
青光眼新型双眼颜色、运动和对比度测试的评估
作者：
F. Rauscher;C. Chisholm;D. Edgar;J. Barbur
青光眼对双眼视觉灵敏度的影响检测各种刺激属性在中央凹和四个副中央视网膜区域进行了研究。该研究采用了一些视觉刺激，旨在隔离各种刺激属性的处理。我们测量绝对对比度检测阈值和功能对比灵敏度使用兰多特环刺激。这种基于Landolt c的检测和间隙辨别的心理物理对比测试使我们能够在距固定点6°的中央凹处进行测试，并采用交叉测试位置进行测试。通过在静态亮度对比噪声中嵌入运动刺激来检测一阶运动感知。用颜色评估和诊断（CAD）测试测量红/绿（RG）和黄/蓝（YB）颜色阈值，该测试利用随机动态亮度对比噪声（±45%）来确保只有颜色而不是亮度信号可用于目标检测。研究对象为正常对照（n = 65）和双眼视野缺损的青光眼患者（n = 15），根据其Humphrey field Analyzer平均偏差（MD）评分进行分类。视觉功能损害随刺激属性和位置的不同而不同。随着青光眼程度的增加，所有测试都发现视力丧失的进展。对于轻度青光眼受试者（MD为- 0.01 dB至- 6.00 dB）， RG颜色阈值超出正常年龄代表范围的数据点明显多于任何其他视觉测试，其次是运动阈值。与中央凹数据相比，中央凹旁数据尤其如此。因此，结合多个位置RG颜色和运动测试的双眼视觉表现的多方面测量可能为青光眼的生活质量测量提供更好的比较指标。
The effects of glaucoma on binocular visual sensitivity for the detection of various stimulus attributes are investigated at the fovea and in four paracentral retinal regions. The study employed a number of visual stimuli designed to isolate the processing of various stimulus attributes. We measured absolute contrast detection thresholds and functional contrast sensitivity by using Landolt ring stimuli. This psychophysical Landolt C-based contrast test of detection and gap discrimination allowed us to test parafoveally at 6 ° from fixation and foveally by employing interleaved testing locations. First-order motion perception was examined by using moving stimuli embedded in static luminance contrast noise. Red/green (RG) and yellow/blue (YB) colour thresholds were measured with the Colour Assessment and Diagnosis (CAD) test, which utilises random dynamic luminance contrast noise (± 45 %) to ensure that only colour and not luminance signals are available for target detection. Subjects were normal controls (n = 65) and glaucoma patients with binocular visual field defects (n = 15) classified based on their Humphrey Field Analyzer mean deviation (MD) scores. The impairment of visual function varied depending on the stimulus attribute and location tested. Progression of loss was noted for all tests as the degree of glaucoma increased. For subjects with mild glaucoma (MD −0.01 dB to −6.00 dB) significantly more data points fell outside the normal age-representative range for RG colour thresholds than for any other visual test, followed by motion thresholds. This was particularly the case for the parafoveal data compared with the foveal data. Thus, a multifaceted measure of binocular visual performance, incorporating RG colour and motion test at multiple locations, might provide a better index for comparison with quality of life measures in glaucoma.
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原发性开角型青光眼和高眼压症患者的运动知觉异常。
影响因子：
4.4
作者：
Silverman,SE;Trick,GL;HartJr,WM
通讯作者：
HartJr,WM
影响因子：
4.4
作者：
Anthony J. Adams;Rosemary Rodic;R. Husted;Robert;Stamper
通讯作者：
Anthony J. Adams;Rosemary Rodic;R. Husted;Robert;Stamper
影响因子：
4.1
作者：
Quigley, HA
通讯作者：
Quigley, HA
影响因子：
4.3
作者：
Fisk, GD;Owsley, C;Mennemeier, M
通讯作者：
Mennemeier, M
影响因子：
--
作者：
JOHNSON, CA;ADAMS, AJ;BRANDT, JD
通讯作者：
BRANDT, JD