Biomechanical characteristics of regenerated cortical bone in the canine mandible.
Biomechanical characteristics of regenerated cortical bone in the canine mandible.
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DOI：
10.1002/term.347
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发表时间：
2011-07
影响因子：
3.3
通讯作者：
Dechow, Paul C.
中科院分区：
文献类型：
--
作者：
Zapata, Uriel;Opperman, Lynne A.;Kontogiorgos, Elias;Elsalanty, Mohammed E.;Dechow, Paul C.
关键词：
为了测试使用下颌骨运输（MBT）牵引产生的再生皮质骨的机械性能，5只成年雄性美国猎狐犬接受了单侧下颌骨牵引，放置了一种新型MBT装置，以线性修复30-35 mm的骨缺损。巩固期开始后12周处死动物。14个圆柱形标本取自重建下颌骨的内（舌）和外（颊）板，21个对照标本取自下颌骨的对侧。采用非破坏性脉冲超声技术对35个圆柱形皮质骨标本的力学性能进行了评估。结果表明，所有的皮质力学性能表现出较高的数值在对照侧比MBT再生侧。此外，无论是密度和弹性模量的最大刚度方向的再生皮质骨标本是在舌侧高于颊侧。有趣的是，在35个皮质样本中，正交方向的弹性模量（E1和E2）之间没有统计学差异。数据表明，再生犬皮质骨不仅是异质的，但弹性力学性能往往近似横向各向同性的组织水平，而不是控制皮质骨是正交各向异性。此外，弹性力学性能不仅在对照侧更高，而且在舌侧解剖位置也更高，这表明重建钢板的存在具有应力屏蔽效应。
To test the mechanical properties of regenerate cortical bone created using Mandibular Bone Transport (MBT) distraction, five adult male American foxhound dogs underwent unilateral distraction of the mandible with a novel MBT device placed to linearly repair a 30-35 mm bone defect. The animals were sacrificed 12 weeks after the beginning of the consolidation period. Fourteen cylindrical specimens were taken from the inner (lingual) and outer (buccal) plates of the reconstructed mandible and 21 control specimens were removed from the contralateral aspect of the mandible. The mechanical properties of the 35 cylindrical cortical bone specimens were assessed by using a non-destructive pulse ultrasound technique. Results showed that all of the cortical mechanical properties exhibit higher numerical values on the control side than the MBT regenerate side. In addition, both densities and the elastic moduli in the direction of maximum stiffness of the regenerate cortical bone specimens are higher on the lingual side than the buccal side. Interestingly, there is no statistical difference between elastic modulus (E1 and E2) in orthogonal directions throughout the 35 cortical specimens. The data suggest that the regenerate canine cortical bone is not only heterogeneous, but the elastic mechanical properties tend to approximate transverse isotropy at a tissue level as opposed to control cortical bone that is orthotropic. In addition, the elastic mechanical properties are not only higher on the control side but also in the lingual anatomical position, suggesting a stress shielding effect from the presence of the reconstruction plate.
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影响因子：
2.4
作者：
ASHMAN, RB;CORIN, JD;TURNER, CH
通讯作者：
TURNER, CH
DOI：
10.1097/00002480-198804000-00005
发表时间：
1988-04-01
期刊：
ASAIO transactions
影响因子：
--
作者：
Anderson, J M
通讯作者：
Anderson, J M
DOI：
10.1002/ar.a.20166
发表时间：
2005-04-01
期刊：
ANATOMICAL RECORD PART A-DISCOVERIES IN MOLECULAR CELLULAR AND EVOLUTIONARY BIOLOGY
影响因子：
--
作者：
Marinescu, R;Daegling, DJ;Rapoff, AJ
通讯作者：
Rapoff, AJ
影响因子：
--
作者：
Imola, Mario J;Hamlar, David D;Chowdhury, Khalid
通讯作者：
Chowdhury, Khalid
DOI：
10.1016/j.ijom.2006.03.018
发表时间：
2006-09-01
影响因子：
2.4
作者：
Kunz, C.;Adolphs, N.;Rahn, B.
通讯作者：
Rahn, B.