Analysis of Consistency in Structural and Functional Connectivity of Human Brain.

Analysis of Consistency in Structural and Functional Connectivity of Human Brain.
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DOI:
10.1109/isbi45749.2020.9098412
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发表时间:
2020-04
期刊:
Proceedings. IEEE International Symposium on Biomedical Imaging
影响因子:
--
通讯作者:
Verma R
Verma R
中科院分区:
其他
文献类型:
--
作者:
Osmanlıoğlu Y;Alappatt JA;Parker D;Verma R

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分析脑的结构和功能连接已成为神经科学研究的基本方法。尽管一些研究报告一致的相似性,以及结构和静息状态(rs)功能连接体的差异,这两种方式之间的连接一致性的比较研究仍然缺乏。尽管如此,包括两种连接类型的连接组学分析需要额外的注意,因为连接的一致性在不同的模式中不同,可能会影响结果的解释。在这项研究中,我们提出了一个全面的分析的一致性结构和rs-功能连接组获得纵向扩散MRI和rs-功能磁共振成像数据的一个单一的健康受试者。我们对比的确定性和概率跟踪的完整,积极和消极的功能连接在各种连接体生成方案的一致性,使用相关性作为一致性的衡量标准。
Analysis of structural and functional connectivity of brain has become a fundamental approach in neuroscientific research. Despite several studies reporting consistent similarities as well as differences for structural and resting state (rs) functional connectomes, a comparative investigation of connectomic consistency between the two modalities is still lacking. Nonetheless, connectomic analysis comprising both connectivity types necessitate extra attention as consistency of connectivity differs across modalities, possibly affecting the interpretation of the results. In this study, we present a comprehensive analysis of consistency in structural and rs-functional connectomes obtained from longitudinal diffusion MRI and rs-fMRI data of a single healthy subject. We contrast consistency of deterministic and probabilistic tracking with that of full, positive, and negative functional connectivities across various connectome generation schemes, using correlation as a measure of consistency.
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