Simultaneous improvement in production of microalgal biodiesel and high-value alpha-linolenic acid by a single regulator acetylcholine.
Simultaneous improvement in production of microalgal biodiesel and high-value alpha-linolenic acid by a single regulator acetylcholine.
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DOI：
10.1186/s13068-015-0196-0
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发表时间：
2015
影响因子：
6.3
通讯作者：
Chen YF
中科院分区：
文献类型：
--
作者：
Parsaeimehr A;Sun Z;Dou X;Chen YF
光合自养微藻是一种很有前途的生物柴油持续生产途径，但目前受到生物质和脂质产量低的影响。我们正在开发一种化学方法，以改善微藻积累的原料脂质以及高价值的α-亚麻酸，这反过来可能会提供一个驱动力的生物柴油生产。我们证明了生物活性小分子“乙酰胆碱”对小球藻生物量、总脂质和α-亚麻酸积累的有效性。不同种类的小球藻都有不同的效果。此外，乙酰胆碱的前体和类似物在较高的应用剂量下显示出增加的有效性，生物质、总脂质和α-亚麻酸分别比对照组最大增加126、80和60%。乙酰胆碱的前体和类似物也提高了计算生物柴油的产量。研究了微藻脂肪酸组成变化对生物柴油品质的影响。如果与目前的遗传方法相结合，这里描述的化学方法可以提高光自养微藻的脂质产量和生物柴油产量。本文的在线版本（doi：10.1186/s13068-015-0196-0）包含补充材料，可供授权用户使用。
Photoautotrophic microalgae are a promising avenue for sustained biodiesel production, but are compromised by low yields of biomass and lipids at present. We are developing a chemical approach to improve microalgal accumulation of feedstock lipids as well as high-value alpha-linolenic acid which in turn might provide a driving force for biodiesel production. We demonstrate the effectiveness of the small bioactive molecule “acetylcholine” on accumulation of biomass, total lipids, and alpha-linolenic acid in Chlorella sorokiniana. The effectiveness exists in different species of Chlorella. Moreover, the precursor and analogs of acetylcholine display increased effectiveness at higher applied doses, with maximal increases by 126, 80, and 60% over controls for biomass, total lipids, and alpha-linolenic acid, respectively. Production of calculated biodiesel was also improved by the precursor and analogs of acetylcholine. The biodiesel quality affected by changes in microalgal fatty acid composition was addressed. The chemical approach described here could improve the lipid yield and biodiesel production of photoautotrophic microalgae if combined with current genetic approaches. The online version of this article (doi:10.1186/s13068-015-0196-0) contains supplementary material, which is available to authorized users.
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影响因子：
10.4
作者：
Demirbas, Ayhan;Demirbas, M. Fatih
通讯作者：
Demirbas, M. Fatih
影响因子：
4.2
作者：
JONES, RS;STUTTE, CA
通讯作者：
STUTTE, CA
影响因子：
3.6
作者：
Nascimento, Iracema Andrade;Izabel Marques, Sheyla Santa;Nascimento, Maurcio Andrade
通讯作者：
Nascimento, Maurcio Andrade
DOI：
10.1128/aem.16.4.620-623.1968
发表时间：
1968-01-01
期刊：
APPLIED MICROBIOLOGY
影响因子：
--
作者：
IKAWA, M;BOROWSKI, PT;CHAKRAVARTI, A
通讯作者：
CHAKRAVARTI, A
影响因子：
3.8
作者：
Oliveira, Eugenio E.;Schleicher, Sabine;Salgado, Vincent L.
通讯作者：
Salgado, Vincent L.