Short-term effectiveness of HIV care coordination among persons with recent HIV diagnosis or history of poor HIV outcomes.
Short-term effectiveness of HIV care coordination among persons with recent HIV diagnosis or history of poor HIV outcomes.
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在近期诊断出艾滋病病毒或有艾滋病病毒感染不良史的人群中，艾滋病护理协调的短期效果。
DOI：
10.1371/journal.pone.0204017
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发表时间：
2018
期刊：
影响因子：
3.7
通讯作者：
Irvine MK
中科院分区：
文献类型：
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作者：
Nash D;Robertson MM;Penrose K;Chamberlin S;Robbins RS;Braunstein SL;Myers JE;Abraham B;Kulkarni S;Waldron L;Levin B;Irvine MK
纽约市艾滋病毒护理协调方案（CCP）结合了多种循证战略，以支持艾滋病毒感染者（PLWH）的风险，或与最近的历史，艾滋病毒结果不佳。我们通过合并CCP客户的计划数据与所有纽约市PLWH的基于人群的监测数据来评估CCP的相对有效性。一个非CCP对照组的类似PLWH谁符合CCP资格标准确定使用监测数据。CCP组和非CCP组在4个基线治疗状态组（新诊断或既往诊断以及持续未抑制、不一致抑制或持续抑制）内的CCP入组倾向上相匹配。我们比较了12个月随访时病毒载量抑制的CCP与非CCP比例。在纳入的13，624人中，15.3%是新诊断的;在84.7%的既往诊断者中，14.2%在基线前一年一直受到抑制，28.9%受到不一致的抑制，41.6%一直未受到抑制。12个月随访时，59·9%的CCP参与者和53·9%的非CCP参与者的病毒载量受到抑制（相对风险= 1.11，95%CI：1.08-1.14）。在新诊断的患者和基线时持续未抑制的患者中，CCP与非CCP参与者的病毒载量抑制相对风险分别为1.15（95%CI：1.09-1.23）和1.32（95%CI：1.23-1.42）。对于新诊断或持续未受抑制的患者，CCP暴露显示出比无CCP暴露的益处，但对于基线前一年受抑制的患者则无益处。我们建议在CCP入组中进行更有针对性的病例发现，并增加对病毒载量抑制维持的关注。
The New York City HIV Care Coordination Program (CCP) combines multiple evidence-based strategies to support persons living with HIV (PLWH) at risk for, or with a recent history of, poor HIV outcomes. We assessed the comparative effectiveness of the CCP by merging programmatic data on CCP clients with population-based surveillance data on all New York City PLWH. A non-CCP comparison group of similar PLWH who met CCP eligibility criteria was identified using surveillance data. The CCP and non-CCP groups were matched on propensity for CCP enrollment within four baseline treatment status groups (newly diagnosed or previously diagnosed and either consistently unsuppressed, inconsistently suppressed or consistently suppressed). We compared CCP to non-CCP proportions with viral load suppression at 12-month follow-up. Among the 13,624 persons included, 15∙3% were newly diagnosed; among the 84∙7% previously diagnosed, 14∙2% were consistently suppressed, 28∙9% were inconsistently suppressed, and 41∙6% were consistently unsuppressed in the year prior to baseline. At 12-month follow-up, 59∙9% of CCP and 53∙9% of non-CCP participants had viral load suppression (Relative Risk = 1.11, 95%CI:1.08–1.14). Among those newly diagnosed and those consistently unsuppressed at baseline, the relative risk of viral load suppression in the CCP versus non-CCP participants was 1.15 (95%CI:1.09–1.23) and 1.32 (95%CI:1.23–1.42), respectively. CCP exposure shows benefits over no CCP exposure for persons newly diagnosed or consistently unsuppressed, but not for persons suppressed in the year prior to baseline. We recommend more targeted case finding for CCP enrollment and increased attention to viral load suppression maintenance.
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影响因子：
3.7
作者：
Finitsis DJ;Pellowski JA;Johnson BT
通讯作者：
Johnson BT
影响因子：
158.5
作者：
Danel, Christine;Moh, Raoul;Anglaret, Xavier
通讯作者：
Anglaret, Xavier
影响因子：
4.6
作者：
Milloy, M. -J.;Marshall, Brandon D. L.;Montaner, Julio;Wood, Evan
通讯作者：
Wood, Evan
影响因子：
4.4
作者：
Charania MR;Marshall KJ;Lyles CM;Crepaz N;Kay LS;Koenig LJ;Weidle PJ;Purcell DW;HIV/AIDS Prevention Research Synthesis (PRS) Team
通讯作者：
HIV/AIDS Prevention Research Synthesis (PRS) Team
DOI：
10.1521/aeap.2012.24.1.1
发表时间：
2012-02
期刊：
AIDS education and prevention : official publication of the International Society for AIDS Education
影响因子：
--
作者：
Bogart LM;Wagner GJ;Mutchler MG;Risley B;McDavitt BW;McKay T;Klein DJ
通讯作者：
Klein DJ