Social support during intensive care unit stay might improve mental impairment and consequently health-related quality of life in survivors of severe acute respiratory distress syndrome.
Social support during intensive care unit stay might improve mental impairment and consequently health-related quality of life in survivors of severe acute respiratory distress syndrome.
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DOI：
10.1186/cc5070
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发表时间：
2006
期刊：
影响因子：
--
通讯作者：
Kaisers U
中科院分区：
文献类型：
--
作者：
Deja M;Denke C;Weber-Carstens S;Schröder J;Pille CE;Hokema F;Falke KJ;Kaisers U
我们调查了急性呼吸窘迫综合征（ARDS）长期幸存者的健康相关生活质量（HRQoL）和创伤后应激障碍（PTSD）的持续症状。我们希望评估创伤后应激障碍对HRQoL的影响，并调查重症监护室（ICU）治疗期间感知的社会支持对创伤后应激障碍症状和HRQoL的影响。在ARDS患者中，我们前瞻性测量HRQoL（医学结局研究36项简表; SF-36）、PTSD症状（创伤后应激综合征10问题量表; PTSS-10）、感知社会支持（社会支持问卷; F-Sozu）和精神病理学症状（症状自评量表-90-R）;并收集社会人口学数据，包括当前就业状况。在129名入组的幸存者中，65名（50.4%）在从ICU出院后平均57 ± 32个月有应答。PTSS-10用于测量PTSD的症状，将ARDS患者分为两个亚组（“高分患者”，表明患者发展PTSD的风险增加，和“低分患者”）。与年龄和性别调整的健康对照组相比，HRQoL在所有维度上均显著降低。18名患者（29%）被确定患有创伤后应激障碍的风险增加。PTSD风险与ICU期间的焦虑显著相关。在这组患者中，存在永久或暂时残疾的趋势，与从ICU出院到进入研究之间的时间无关。感知的社会支持与PTSD症状的减轻相关（Pearson相关; p < 0.05）。事后检验显示，“高分患者”和“低分患者”在心理健康方面存在显着差异，尽管他们在身体尺寸上没有差异。HRQoL在长期生存者中降低，并且与慢性PTSD的风险增加相关，随后发生心理疾病。这与身体状况无关，与他们在ICU住院期间焦虑的创伤记忆有关。社会支持可能会改善心理健康，从而改善长期结果，包括就业状况。
We investigated health-related quality of life (HRQoL) and persistent symptoms of post-traumatic stress disorder (PTSD) in long-term survivors of acute respiratory distress syndrome (ARDS). We wished to evaluate the influence of PTSD on HRQoL and to investigate the influence of perceived social support during intensive care unit (ICU) treatment on both PTSD symptoms and HRQoL. In ARDS patients we prospectively measured HRQoL (Medical Outcomes Study 36-Item Short Form; SF-36), symptoms of PTSD (Post-Traumatic Stress Syndrome 10-Questions Inventory; PTSS-10), perceived social support (Questionnaire for Social Support; F-Sozu) and symptoms of psychopathology (Symptom Checklist-90-R); and collected sociodemographic data including current employment status. Sixty-five (50.4%) out of 129 enrolled survivors responded, on average 57 ± 32 months after discharge from ICU. Measuring symptoms of PTSD the PTSS-10 was used to divide the ARDS patients into two subgroups ('high-scoring patients', indicating patients with an increased risk for developing PTSD, and 'low-scoring patients'). HRQoL was significantly reduced in all dimensions in comparison with age- and gender-adjusted healthy controls. Eighteen patients (29%) were identified as being at increased risk for PTSD. PTSD risk was significantly linked with anxiety during their ICU stay. In this group of patients there was a trend towards permanent or temporary disability, independent of the period between discharge from ICU and study entry. Perceived social support was associated with a reduction in PTSD symptoms (Pearson correlation; p < 0.05). Post-hoc test revealed a significant difference between 'high-scoring patients' and 'low-scoring patients' with respect to mental health, although they did not differ in physical dimensions. HRQoL was reduced in long-term survivors, and was linked with an increased risk of chronic PTSD with ensuing psychological morbidity. This was independent of physical condition and was associated with traumatic memories of anxiety during their ICU stay. Social support might improve mental health and consequently long-term outcome including employment status.
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影响因子：
--
作者：
KESSLER, RC;SONNEGA, A;NELSON, CB
通讯作者：
NELSON, CB
影响因子：
10.7
作者：
Chrispin, PS;Scotton, H;Ridley, SA
通讯作者：
Ridley, SA
影响因子：
8.8
作者：
Schnyder, U;Mörgeli, H;Buddeberg, C
通讯作者：
Buddeberg, C
影响因子：
3
作者：
MCHORNEY, CA;WARE, JE;RACZEK, AE
通讯作者：
RACZEK, AE
影响因子：
38.9
作者：
Cuthbertson, BH;Hull, A;Scott, J
通讯作者：
Scott, J